Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CLK1 | P49759 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060136 | 0.90 | HTT (0.69) | HTTGAAKDM4EMAPTTDP1 | |
| SCHEMBL4066324 | 0.87 | CLK1 (0.69) | HTTGAAKDM4EMAPTTDP1 | |
| SCHEMBL4065608 | 0.80 | HTT (1.00) | HTTGAAKDM4EMAPTTDP1 | |
| SCHEMBL4063240 | 0.73 | HTT (0.58) | HTTGAAKDM4EMAPTTDP1 | |
| SCHEMBL4059114 | 0.73 | MAPT (1.00) | HTTGAAKDM4EMAPTTDP1 | |
| SCHEMBL4795234 | 0.70 | CLK1 (0.85) | HTTGAAKDM4EMAPTTDP1 | |
| SCHEMBL4066988 | 0.70 | HTT (1.00) | HTTGAAKDM4EMAPTTDP1 | |
| SCHEMBL28107505 | 0.69 | HTT (0.56) | HTTGAAKDM4EMAPTTDP1 | |
| SCHEMBL4071064 | 0.68 | HTT (0.81) | HTTGAAKDM4EMAPTTDP1 | |
| Acetic Acid SCHEMBL4066978 | 0.68 | CLK1 (0.91) | HTTGAAKDM4EMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960777-B1 | SERUM-FREE EXPANSION OF CELLS IN CULTURE | CHOONGWAE PHARMA CORP (KR) | 2009-10-21 | — | — | EP | disclosed |
| US-20070128669-A1 | Serum-free expansion of cells in culture | INSTITUTE FOR CHEMICAL GENOMICS (US) | 2007-06-07 | — | — | US | disclosed |