Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1151186 | 0.87 | TSHR (0.55) | TSHRHPGDMAPTALDH1A1TP53 | |
| SCHEMBL7761807 | 0.87 | TSHR (0.55) | TSHRHPGDMAPTALDH1A1TP53 | |
| SCHEMBL13397834 | 0.86 | TSHR (0.63) | TSHRHPGDMAPTALDH1A1TP53 | |
| SCHEMBL30589890 | 0.85 | TSHR (0.73) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL268430 | 0.85 | TSHR (0.73) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL21444212 | 0.84 | TSHR (0.53) | TSHRHPGDMAPTALDH1A1TP53 | |
| SCHEMBL23647296 | 0.84 | TSHR (0.52) | TSHRMAPTALDH1A1CYP3A4PRKCA | |
| SCHEMBL7761789 | 0.84 | TSHR (0.52) | TSHRHPGDMAPTALDH1A1CYP3A4 | |
| SCHEMBL27245506 | 0.83 | TSHR (0.47) | TSHRHPGDMAPTALDH1A1TP53 | |
| Ethylene SCHEMBL8565034 | 0.83 | TSHR (0.70) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158302-A2 | VISCOUS ALPHA-CYANOACRYLATE COMPOSITIONS | CLOSURE MEDICAL CORPORATION (US) | 2009-12-30 | — | — | WO | disclosed |