Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL11703442 | 0.92 | ESR1 (0.48) | ESR1ADORA3SLC6A2SLC6A3LMNA | |
| SCHEMBL28063717 | 0.92 | ESR1 (0.48) | ESR1ADORA3SLC6A2SLC6A3LMNA | |
| Hydrogen Sulfide SCHEMBL11761473 | 0.91 | ESR1 (0.47) | ESR1ADORA3SLC6A2SLC6A3LMNA | |
| Hydrogen Sulfide SCHEMBL11700863 | 0.91 | ESR1 (0.47) | ESR1ADORA3SLC6A2SLC6A3LMNA | |
| Hydrogen Sulfide SCHEMBL11703914 | 0.91 | ESR1 (0.47) | ESR1ADORA3SLC6A2SLC6A3LMNA | |
| Hydrogen Sulfide SCHEMBL11700299 | 0.91 | ESR1 (0.47) | ESR1ADORA3SLC6A2SLC6A3LMNA | |
| Hydrogen Sulfide SCHEMBL11704189 | 0.91 | ESR1 (0.47) | ESR1ADORA3SLC6A2SLC6A3LMNA | |
| Hydrogen Sulfide SCHEMBL11704184 | 0.91 | ESR1 (0.47) | ESR1ADORA3SLC6A2SLC6A3LMNA | |
| SCHEMBL28771612 | 0.83 | BDKRB2 (0.47) | LMNACYP3A4CYP1A2CYP2D6MAPT | |
| SCHEMBL7640359 | 0.82 | HRH3 (0.45) | TDP1ALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104530475-B | Preparation method of multifunctional synergistic antioxidative stabilizer | 绍兴瑞康生物科技有限公司 | 2017-05-10 | — | — | CN | disclosed |
| EP-2051964-A2 | FATTY ACID AMIDE HYDROLASE INHIBITORS | University of Connecticut (US) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008013963-A2 | FATTY ACID AMIDE HYDROLASE INHIBITORS | UNIVERSITY OF CONNECTICUT (US) | 2008-01-31 | — | — | WO | disclosed |