Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 2/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10022977 | 0.74 | NOS1 (0.52) | NOS1SMN1; SMN2ALDH1A1POLBADORA2A | |
| SCHEMBL4138997 | 0.72 | KDM4E (0.58) | SMN1; SMN2KDM4EALDH1A1AOC3GAA | |
| SCHEMBL4153015 | 0.71 | KMT2A (0.53) | SMN1; SMN2ALDH1A1POLBKMT2AGAA | |
| SCHEMBL12777780 | 0.69 | DCK (0.49) | NOS1KDM4EADORA2AADORA1AOC3 | |
| SCHEMBL23176648 | 0.68 | MAPT (0.62) | SMN1; SMN2KDM4EALDH1A1POLBKMT2A | |
| SCHEMBL14451013 | 0.68 | KDM4E (0.54) | SMN1; SMN2HSD17B10KDM4EALDH1A1POLB | |
| SCHEMBL427731 | 0.68 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4EALDH1A1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL28463715 | 0.67 | KDM4E (0.53) | SMN1; SMN2HSD17B10KDM4EALDH1A1POLB | |
| SCHEMBL3894243 | 0.67 | ADORA2A (0.37) | NOS1KDM4EKMT2AADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL3265116 | 0.67 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2104566-A1 | OLEFIN METATHESIS INITIATORS BEARING THIAZOL-2-YLIDENE LIGANDS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2009-09-30 | — | — | EP | disclosed |
| WO-2008064223-A1 | OLEFIN METATHESIS INITIATORS BEARING THIAZOL-2-YLIDENE LIGANDS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-05-29 | — | — | WO | disclosed |