SCHEMBL4059956

SCHEMBL4059956

OCC(CO)N[C@H](CO)c1n[nH]c2cncnc12

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PNP P00491 1/20 0.35
MTAP Q13126 1/20 0.34
GRM4 Q14833 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2611031 0.71 GRM4 (0.37) GRM4
SCHEMBL24983629 0.69 GRM4 (0.34) GRM4
SCHEMBL1948863 0.68 PNP (0.63) PNP
SCHEMBL1947631 0.68 PNP (0.63) PNP
SCHEMBL352379 0.65 GRM4 (0.39) GRM4
SCHEMBL473390 0.65 GRM4 (0.46) GRM4
SCHEMBL4053163 0.63 PNP (0.36) PNPGRM4
SCHEMBL325244 0.63 HCAR2 (0.36) GRM4
SCHEMBL421235 0.61 DYRK1A (0.52) GRM4
SCHEMBL11874314 0.61 GRM4 (0.39) GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008030119-A9 ACYCLIC AMINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND HYDROLASES INDUSTRIAL RESEARCH LIMITED (NZ) 2009-09-24 WO disclosed
EP-2057165-A1 ACYCLIC AMINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND HYDROLASES INDUSTRIAL RESEARCH LIMITED (NZ) 2009-05-13 EP disclosed
WO-2008030119-A1 ACYCLIC AMINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND HYDROLASES INDUSTRIAL RESEARCH LIMITED (NZ) 2008-03-13 WO disclosed