Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.50 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.50 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.50 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.50 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.50 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.50 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 4/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8785132 | 1.00 | MAOB (0.62) | MAOBRAB9APSEN1PSEN2APH1B | |
| SCHEMBL11614936 | 0.88 | RAB9A (0.69) | MAOBRAB9AMAOAALDH1A1SMN1; SMN2 | |
| SCHEMBL23223734 | 0.88 | RAB9A (0.69) | MAOBRAB9AMAOAALDH1A1SMN1; SMN2 | |
| SCHEMBL18664184 | 0.86 | MAOB (0.81) | MAOBRAB9AMAOAHRH3SMPD1 | |
| SCHEMBL29741480 | 0.86 | MAOB (0.81) | MAOBRAB9AMAOAHRH3SMPD1 | |
| SCHEMBL5994318 | 0.84 | ALDH1A1 (0.54) | MAOBRAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL15383165 | 0.83 | MAOB (0.62) | MAOBRAB9APSEN1PSEN2APH1B | |
| SCHEMBL22238265 | 0.83 | MAOB (0.62) | MAOBRAB9APSEN1PSEN2APH1B | |
| SCHEMBL9034561 | 0.83 | MAOB (0.68) | MAOBRAB9ASPHK2SPHK1MAOA | |
| SCHEMBL9842136 | 0.82 | MAOB (0.65) | MAOBRAB9AMAOASMN1; SMN2SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107151220-B | Phenol compound containing benzyloxy phenyl, preparation method and application thereof | 中国医学科学院药物研究所 | 2021-07-20 | — | — | CN | disclosed |
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |
| EP-0365328-B1 | Pyridine derivatives | ZENECA LTD (GB) | 1996-04-03 | — | — | EP | disclosed |
| US-5053415-A | Antiischemic, antiinflammatory, antiarthritic agents, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-01 | — | — | US | disclosed |
| EP-0365328-A2 | Pyridine derivatives | ZENECA LIMITED (GB) | 1990-04-25 | — | — | EP | disclosed |