Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22068158 | 0.84 | IDO1 (0.55) | MAP4K4IDO1MAPTADORA2BADORA2A | |
| SCHEMBL18161083 | 0.81 | IDO1 (0.46) | MAP4K4IDO1MAPTADORA2BADORA2A | |
| SCHEMBL28480049 | 0.79 | ESR2 (0.48) | IDO1MAPTADORA2BALOX5 | |
| SCHEMBL240826 | 0.79 | TAAR1 (0.48) | MAP4K4IDO1MAPTADORA2BADORA2A | |
| SCHEMBL19759543 | 0.79 | ROCK2 (0.44) | MAP4K4IDO1MAPTMAPK13MAPK12 | |
| SCHEMBL16242324 | 0.78 | MAP4K4 (0.62) | MAP4K4MAPTALOX5GCGRAHR | |
| SCHEMBL3500189 | 0.78 | MAP4K4 (0.49) | MAP4K4IDO1MAPTADORA2AALOX5 | |
| SCHEMBL21333215 | 0.78 | NOTUM (0.48) | MAP4K4IDO1MAPTADORA2BMINK1 | |
| SCHEMBL31472663 | 0.78 | NOTUM (0.48) | MAP4K4IDO1MAPTADORA2BMINK1 | |
| SCHEMBL5452118 | 0.76 | ADORA2B (0.42) | IDO1MAPTADORA2BADORA2AMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120655-A1 | INDOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 2009-10-01 | — | — | WO | disclosed |