Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27789125 | 0.86 | KDM4E (0.61) | KDM4EALDH1A1POLBMEN1KMT2A | |
| SCHEMBL15763177 | 0.85 | KDM4E (0.59) | KDM4EALDH1A1POLBGAAMEN1 | |
| SCHEMBL2907506 | 0.84 | HDAC1 (0.65) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL2912150 | 0.83 | HRH3 (0.64) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL30577945 | 0.81 | MEN1 (0.57) | KDM4EALDH1A1GAAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27587927 | 0.81 | HRH3 (0.62) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL3920368 | 0.80 | SIGMAR1 (0.56) | GAAMEN1KMT2AHDAC1 | |
| SCHEMBL2912823 | 0.80 | HPGD (0.64) | KDM4EALDH1A1KMT2A | |
| SCHEMBL18173307 | 0.80 | MEN1 (0.62) | GAAMEN1KMT2AHDAC1HDAC8 | |
| SCHEMBL2776747 | 0.80 | ALDH1A1 (0.59) | ALDH1A1POLBGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034390-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE IN TREATING HEPATITIS C | ARROW THERAPEUTICS LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |