Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060402 | 1.00 | MEN1 (0.47) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL4060296 | 0.88 | DHODH (0.43) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL4060291 | 0.88 | DHODH (0.43) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL4058655 | 0.85 | NPSR1 (0.52) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL4058649 | 0.85 | NPSR1 (0.52) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL4057733 | 0.82 | GAA (0.43) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL4057737 | 0.82 | GAA (0.43) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL9181743 | 0.78 | MEN1 (0.46) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL28977478 | 0.78 | ALDH1A1 (0.51) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL5807773 | 0.77 | PIN1 (0.57) | MEN1KMT2APOLBALDH1A1PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110655-A1 | NOVEL BETA SUBSTITUTED MORITA-BAYLIS-HILLMAN DERIVATIVES | SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) | 2009-09-11 | — | — | WO | claimed |
| WO-2009110655-A1 | NOVEL BETA SUBSTITUTED MORITA-BAYLIS-HILLMAN DERIVATIVES | SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) | 2009-09-11 | — | — | WO | disclosed |