Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.46 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4061598 | 0.83 | P2RX3 (0.62) | P2RX3P2RX2DHFRPOLBGAA | |
| SCHEMBL27316536 | 0.83 | P2RX3 (0.53) | P2RX3P2RX2DHFRPOLBGAA | |
| SCHEMBL4068175 | 0.81 | P2RX3 (0.47) | P2RX3P2RX2DHFRPOLBGAA | |
| SCHEMBL4061388 | 0.78 | P2RX3 (0.46) | P2RX3P2RX2DHFRPOLBGAA | |
| SCHEMBL4071802 | 0.78 | P2RX3 (0.47) | P2RX3P2RX2 | |
| SCHEMBL16712950 | 0.77 | CTSA (0.48) | DHFR | |
| SCHEMBL19997093 | 0.75 | LPAR1 (0.40) | P2RX3P2RX2POLBGAAGFER | |
| SCHEMBL9254425 | 0.75 | ERN1 (0.49) | DHFR | |
| SCHEMBL84489 | 0.74 | LPAR1 (0.50) | POLBGAAGFERTHRBRORC | |
| SCHEMBL1911429 | 0.74 | LPAR1 (0.50) | POLBGAAGFERLPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |