Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.47 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4071802 | 0.91 | P2RX3 (0.47) | P2RX3P2RX2PTGS2PDGFRBPDGFRA | |
| SCHEMBL4061388 | 0.88 | P2RX3 (0.46) | P2RX3P2RX2PTGS2PTGS1POLB | |
| SCHEMBL4061598 | 0.84 | P2RX3 (0.62) | P2RX3P2RX2PDGFRBPDGFRAPOLB | |
| SCHEMBL4072687 | 0.82 | HSD17B10 (0.48) | P2RX3P2RX2POLBDHFRAKR1C3 | |
| SCHEMBL4060460 | 0.81 | P2RX3 (0.46) | P2RX3P2RX2POLBGAAGFER | |
| SCHEMBL13848420 | 0.79 | ROCK1 (0.43) | P2RX3P2RX2POLBGAA | |
| SCHEMBL27316536 | 0.77 | P2RX3 (0.53) | P2RX3P2RX2POLBGAAGFER | |
| SCHEMBL12190521 | 0.75 | GAA (0.50) | P2RX3P2RX2POLBGAAGFER | |
| SCHEMBL13848474 | 0.75 | KCNK3 (0.51) | — | |
| SCHEMBL13816282 | 0.74 | P2RX3 (0.52) | P2RX3P2RX2PDGFRBPDGFRAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |