Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021479 | 0.89 | SMN1; SMN2 (0.64) | ALDH1A1RECQLL3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL26313592 | 0.83 | ALDH1A1 (0.58) | ALDH1A1RECQLL3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL4053916 | 0.82 | ALDH1A1 (0.48) | ALDH1A1RECQLL3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL4053914 | 0.82 | ALDH1A1 (0.48) | ALDH1A1RECQLL3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL7506870 | 0.77 | ALDH1A1 (0.52) | ALDH1A1RECQLL3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL1421294 | 0.77 | SMN1; SMN2 (0.68) | ALDH1A1L3MBTL1SMN1; SMN2TSHRLMNA | |
| SCHEMBL2854838 | 0.76 | SMN1; SMN2 (0.63) | ALDH1A1SMN1; SMN2TSHRLMNAMEN1 | |
| SCHEMBL19049437 | 0.76 | SMN1; SMN2 (0.63) | ALDH1A1SMN1; SMN2TSHRLMNAMEN1 | |
| SCHEMBL13286885 | 0.75 | SERPINE1 (0.64) | ALDH1A1L3MBTL1SMN1; SMN2TSHRLMNA | |
| SCHEMBL3653439 | 0.75 | MEN1 (0.65) | ALDH1A1L3MBTL1SMN1; SMN2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111260-A1 | PHENYLSULFONAMIDE-SUBSTITUTED, PYRAZOLO[1, 5-A]PYRIMIDINES, METHODS FOR PREPARATION AND USES THEREOF | WYETH (US) | 2009-09-11 | — | — | WO | disclosed |