Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 6/20 | 0.55 |
| ▸ | CA9 | Q16790 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.55 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.55 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.55 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.55 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092422 | 0.88 | CA9 (0.68) | ALDH1A1TSHRGAAMAPTMAPK1 | |
| SCHEMBL7021479 | 0.88 | SMN1; SMN2 (0.64) | ALDH1A1TSHRMAPTMAPK1NPSR1 | |
| SCHEMBL18767224 | 0.84 | MAPT (0.55) | ALDH1A1TSHRGAAMAPTMAPK1 | |
| SCHEMBL4060524 | 0.83 | ALDH1A1 (0.55) | ALDH1A1TSHRGAAMAPTNPSR1 | |
| SCHEMBL11348726 | 0.82 | CA9 (0.52) | ALDH1A1TSHRGAAMAPTMAPK1 | |
| SCHEMBL13651238 | 0.81 | CA9 (0.76) | ALDH1A1NPSR1CA12CA9SMN1; SMN2 | |
| SCHEMBL3653439 | 0.79 | MEN1 (0.65) | ALDH1A1TSHRGAAMAPTSMN1; SMN2 | |
| SCHEMBL11354745 | 0.79 | CA9 (0.52) | ALDH1A1TSHRGAAMAPTMAPK1 | |
| SCHEMBL15838841 | 0.79 | ALDH1A1 (0.66) | ALDH1A1TSHRGAAMAPTMAPK1 | |
| SCHEMBL4050803 | 0.78 | ALDH1A1 (0.50) | ALDH1A1GAASMN1; SMN2RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257357-A1 | PROBENECID COMPOUNDS FOR THE TREATMENT OF INFLAMMASOME-MEDIATED LUNG DISEASE | BACAINN BIOTHERAPEUTICS, LTD. (KY) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257357-A1 | PROBENECID COMPOUNDS FOR THE TREATMENT OF INFLAMMASOME-MEDIATED LUNG DISEASE | NLRP3, PYCARD, NLRP1 | ALDH1A1 1247/4885TSHR 4813/4885GAA 2886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.