Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4053151 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL4053154 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL13778887 | 0.82 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2SOAT1HSD11B1CCR1 | |
| SCHEMBL4056342 | 0.82 | SMN1; SMN2 (0.59) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL13980344 | 0.82 | SMN1; SMN2 (0.59) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL9373947 | 0.82 | SMN1; SMN2 (0.59) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL8125732 | 0.81 | SOAT1 (0.53) | ALDH1A1MAPTSMN1; SMN2LMNASOAT1 | |
| SCHEMBL6651639 | 0.81 | SOAT1 (0.53) | ALDH1A1MAPTSMN1; SMN2LMNASOAT1 | |
| SCHEMBL6651637 | 0.81 | SOAT1 (0.53) | ALDH1A1MAPTSMN1; SMN2LMNASOAT1 | |
| SCHEMBL4168197 | 0.80 | SMN1; SMN2 (0.40) | SMN1; SMN2SOAT1HSD11B1CCR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118750-A1 | STEREOSELECTIVE HYDROLYSIS FOR THE RESOLUTION OF RACEMIC MIXTURES OF (+/-) -CIS-S-ACETOXY-L- (4-METHOXYPHENYL) -4- (2-FURYL) -2-AZETIDINONE, (+/-) -CIS-S-ACETOXY-L- (4-METHOXYPHENYL) -4- (2-THIENYL) -2-AZETIDINONE, OR | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-10-01 | — | — | WO | disclosed |