Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.76 |
| ▸ | MAPT | P10636 | 6/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | APAF1 | O14727 | 1/20 | 0.56 |
| ▸ | TDP2 | O95551 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | GBA1 | P04062 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL2858469 | 0.98 | GAA (0.73) | GAAMAPTALDH1A1L3MBTL1KDM4E | |
| Sulfuric Acid SCHEMBL28117445 | 0.91 | GAA (0.63) | GAAMAPTALDH1A1L3MBTL1KDM4E | |
| Acetic Acid SCHEMBL10672568 | 0.91 | MAPT (0.63) | GAAMAPTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL11112945 | 0.88 | GAA (0.70) | GAAMAPTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL1030950 | 0.87 | GAA (1.00) | GAAMAPTALDH1A1L3MBTL1KDM4E | |
| Anisole SCHEMBL8779841 | 0.86 | GAA (0.57) | GAAMAPTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL15209705 | 0.85 | RAB9A (0.57) | GAAMAPTALDH1A1L3MBTL1MEN1 | |
| SCHEMBL5605088 | 0.85 | GAA (0.66) | GAAMAPTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL7128297 | 0.83 | GAA (0.50) | GAAMAPTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL11502052 | 0.83 | GAA (0.68) | GAAMAPTALDH1A1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030554-B1 | PIPERIDINE UREA DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-02-28 | — | — | EP | claimed |
| US-9770446-B2 | Piperidine urea derivatives | MERCK PATENT GMBH (DE) | 2017-09-26 | — | — | US | claimed |
| US-20160184285-A1 | PIPERIDINE UREA DERIVATIVES | MERCK PATENT GMBH (DE) | 2016-06-30 | — | — | US | claimed |
| EP-3030554-A1 | PIPERIDINE UREA DERIVATIVES | Merck Patent GmbH (DE) | 2016-06-15 | — | — | EP | claimed |
| WO-2015018475-A1 | PIPERIDINE UREA DERIVATIVES | MERCK PATENT GMBH (DE) | 2015-02-12 | — | — | WO | claimed |
| EP-1655017-B1 | Use of compounds of the type organosilane for dyeing keratinic fibres | OREAL (FR) | 2009-12-30 | — | — | EP | claimed |
| EP-1066282-A1 | NOVEL CATIONIC DI-METHYLENEDIOXY-BENZENES, THEIR USE FOR OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2001-01-10 | — | — | EP | claimed |
| WO-2000043389-A1 | NOVEL CATIONIC DI-METHYLENEDIOXY-BENZENES, THEIR USE FOR OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2000-07-27 | — | — | WO | claimed |
| WO-2025069043-A1 | SUSTAINABLE COMPOSITIONS AND METHODS FOR DYEING AND/OR LIGHTENING KERATIN FIBRES | L'OREAL (FR) | 2025-04-03 | — | — | WO | disclosed |
| EP-4362892-A1 | COMPOSITION COMPRISING AT LEAST ONE ALKYL (POLY)GLYCOSIDE, AT LEAST ONE FATTY ALCOHOL, AT LEAST ONE FATTY ACID, AND AT LEAST ONE ALKALINE AGENT | L'OREAL (FR) | 2024-05-08 | — | — | EP | disclosed |
| CN-115073311-B | Efficient preparation of N, N ′ Synthesis method of-di (2-hydroxyethyl) aniline | 河南大学 | 2023-05-23 | — | — | CN | disclosed |
| EP-4171482-A1 | PRETREATMENT COMPOSITION OF A PROCESS FOR DYEING OR BLEACHING KERATIN FIBERS | L'OREAL (FR) | 2023-05-03 | — | — | EP | disclosed |
| EP-4171490-A1 | PROCESS FOR TREATING KERATIN FIBERS USING PARTICULAR AMINO ACIDS IN HIGH CONCENTRATION | L'OREAL (FR) | 2023-05-03 | — | — | EP | disclosed |
| WO-2023275204-A1 | COMPOSITION COMPRISING AT LEAST ONE ALKYL (POLY)GLYCOSIDE, AT LEAST ONE FATTY ALCOHOL, AT LEAST ONE FATTY ACID, AND AT LEAST ONE ALKALINE AGENT | L'OREAL (FR) | 2023-01-05 | — | — | WO | disclosed |
| EP-0752451-A1 | The use of novel and known 4,5-dihydro-1H-1,2,3-triazolium cationic compounds as dyestuffs and novel 4,5-dihydro-1H-1,2,3-triazolium cationic compounds | BAYER AG (DE) | 1997-01-08 | — | — | EP | disclosed |
| US-4916236-A | CONTACTING VAPOR PHASE MIXTURE OF N-(B-HYDROXY) ALKYLANILINE, WATER AND ACATALYST, COOLING AND CONDENSING | MITSUI TOATSU CHEMICALS, INC. (JP) | 1990-04-10 | — | — | US | disclosed |
| US-4788277-A | OXIDATIVE COUPLING, CATALYST CONTAINING COPPER, DIAMINE, HALOGEN | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1988-11-29 | — | — | US | disclosed |
| EP-0233139-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1987-08-19 | — | — | EP | disclosed |
| EP-0177326-A2 | 2-Arylmethyl-5-aryl-oxazolidines, their preparation and use | SMITHKLINE BEECHAM CORPORATION (US) | 1986-04-09 | — | — | EP | disclosed |
| US-4070357-A | Process for the preparation of indoline derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DT) | 1978-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160184285-A1 | PIPERIDINE UREA DERIVATIVES | PRMT1, TNKS, PRMT3 | GAA 3002/4885MAPT 3205/4885ALDH1A1 1022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.