Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4051755 | 1.00 | MEN1 (0.49) | MEN1KMT2AMMP8CASP1LMNA | |
| SCHEMBL4048528 | 0.88 | DHODH (0.44) | MEN1KMT2ACASP1LMNAMAPT | |
| SCHEMBL4061472 | 0.88 | DHODH (0.44) | MEN1KMT2ACASP1LMNAMAPT | |
| SCHEMBL4019614 | 0.86 | MEN1 (0.47) | MEN1KMT2AMMP8CASP1LMNA | |
| SCHEMBL4062017 | 0.85 | MEN1 (0.50) | MEN1KMT2ACASP1LMNAMAPT | |
| SCHEMBL4056870 | 0.85 | ALDH1A1 (0.44) | MEN1KMT2ACASP1LMNAMAPT | |
| SCHEMBL4060289 | 0.85 | ALDH1A1 (0.44) | MEN1KMT2ACASP1LMNAMAPT | |
| SCHEMBL4057202 | 0.85 | MEN1 (0.50) | MEN1KMT2ACASP1LMNAMAPT | |
| SCHEMBL4049872 | 0.85 | MAPT (0.50) | MEN1KMT2ACASP1LMNAMAPT | |
| SCHEMBL4051074 | 0.85 | MAPT (0.50) | MEN1KMT2ACASP1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110655-A1 | NOVEL BETA SUBSTITUTED MORITA-BAYLIS-HILLMAN DERIVATIVES | SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) | 2009-09-11 | — | — | WO | claimed |
| WO-2009110655-A1 | NOVEL BETA SUBSTITUTED MORITA-BAYLIS-HILLMAN DERIVATIVES | SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) | 2009-09-11 | — | — | WO | disclosed |