SCHEMBL4062308

SCHEMBL4062308

Oc1ccccc1Cc1ccc(O)c(Cc2ccccc2O)c1Cc1ccccc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.67
KEAP1 Q14145 1/20 0.48
TSHR P16473 2/20 0.43
HIF1A Q16665 2/20 0.43
CYP2D6 P10635 1/20 0.43
TAAR1 Q96RJ0 1/20 0.42
AKR1B1 P15121 1/20 0.42
CA12 O43570 5/20 0.41
CA2 P00918 5/20 0.41
IDO1 P14902 3/20 0.41
CA9 Q16790 4/20 0.39
CYP1A2 P05177 2/20 0.39
HSD17B10 Q99714 2/20 0.39
MPO P05164 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
SLC22A1 O15245 1/20 0.38
USP2 O75604 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4063843 0.87 HSPA5 (0.73) HSPA5KEAP1TSHRHIF1ACYP2D6
SCHEMBL9063157 0.85 HSPA5 (0.76) HSPA5KEAP1TSHRHIF1ACYP2D6
SCHEMBL1836697 0.82 HSPA5 (0.43) HSPA5KEAP1TAAR1CYP1A2HSD17B10
SCHEMBL1836194 0.82 HSPA5 (0.43) HSPA5AKR1B1CYP1A2HSD17B10CYP2C9
SCHEMBL30957383 0.82 HSPA5 (0.43) HSPA5KEAP1TAAR1CYP1A2HSD17B10
SCHEMBL49745 0.82 HSPA5 (1.00) HSPA5KEAP1TSHRHIF1ACYP2D6
SCHEMBL29357407 0.82 HSPA5 (1.00) HSPA5KEAP1TSHRHIF1ACYP2D6
SCHEMBL4064773 0.82 HSPA5 (0.64) HSPA5KEAP1TSHRHIF1ACYP2D6
SCHEMBL1843165 0.80 HSPA5 (0.41) HSPA5CYP1A2HSD17B10CYP2C9CYP2C19
SCHEMBL29839938 0.79 HSPA5 (0.94) HSPA5KEAP1TSHRHIF1ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM HSPA5 4266/4885KEAP1 1098/4885TSHR 4402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.