SCHEMBL49745

SCHEMBL49745

Oc1ccccc1Cc1ccccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 1.00
KEAP1 Q14145 1/20 0.65
HIF1A Q16665 2/20 0.59
TSHR P16473 2/20 0.59
CYP2D6 P10635 1/20 0.59
TAAR1 Q96RJ0 1/20 0.56
AKR1B1 P15121 1/20 0.56
CA12 O43570 7/20 0.54
CA2 P00918 7/20 0.54
IDO1 P14902 2/20 0.54
KDM4E B2RXH2 2/20 0.53
HSD17B10 Q99714 2/20 0.53
NPC1 O15118 1/20 0.53
GMNN O75496 1/20 0.53
ALDH1A1 P00352 1/20 0.53
EGFR P00533 1/20 0.53
LMNA P02545 1/20 0.53
FYN P06241 1/20 0.53
POLB P06746 1/20 0.53
CA3 P07451 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29357407 1.00 HSPA5 (1.00) HSPA5KEAP1HIF1ATSHRCYP2D6
Ammonia Solution, Strong SCHEMBL28323965 0.97 HSPA5 (0.94) HSPA5KEAP1HIF1ATSHRCYP2D6
SCHEMBL5852726 0.97 HSPA5 (0.94) HSPA5KEAP1HIF1ATSHRCYP2D6
SCHEMBL7809667 0.97 HSPA5 (0.94) HSPA5KEAP1HIF1ATSHRCYP2D6
SCHEMBL29839938 0.97 HSPA5 (0.94) HSPA5KEAP1HIF1ATSHRCYP2D6
Ethylene Glycol SCHEMBL28140490 0.92 HSPA5 (0.84) HSPA5KEAP1HIF1ATSHRCYP2D6
SCHEMBL30874252 0.89 HSPA5 (0.80) HSPA5KEAP1HIF1ATSHRCYP2D6
SCHEMBL8926581 0.89 HSPA5 (0.80) HSPA5KEAP1HIF1ATSHRCYP2D6
SCHEMBL5852506 0.89 HSPA5 (0.80) HSPA5KEAP1HIF1ATSHRCYP2D6
SCHEMBL54577 0.89 HSPA5 (0.80) HSPA5KEAP1HIF1ATSHRCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10174 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642829-B1 EPOXIDE-BASED COMPOSITION EVONIK OPERATIONS GMBH (DE) 2026-05-27 EP claimed
US-12624152-B2 Curable compositions PPG INDUSTRIES OHIO, INC. (US) 2026-05-12 US claimed
EP-4509574-B1 ADHESIVE AGENT FOR MEDICAL DEVICES, CURED ARTICLE, MEDICAL DEVICE MEMBER, MEDICAL DEVICE, AND METHOD FOR MANUFACTURING MEDICAL DEVICE FUJIFILM CORP (JP) 2026-04-22 EP claimed
EP-3559073-B1 LATENT CURING ACCELERATORS HUNTSMAN ADV MAT SWITZERLAND (CH) 2026-04-08 EP claimed
EP-4049841-B1 HYBRID RESIN COMPOSITION CUBICURE GMBH (AT) 2026-03-18 EP claimed
EP-4705371-A1 USE OF A TERTIARY AMINE IN ORDER TO IMPROVE PROPERTIES OF A CHEMICAL WALL PLUG Hilti Aktiengesellschaft (LI) 2026-03-11 EP claimed
US-12522550-B2 Method for preparing a solid form of bisphenol F ADITYA BIRLA CHEMICALS (THAILAND) LTD. (ADVANCED MATERIALS) (TH) 2026-01-13 US claimed
EP-3673019-B1 ADHESION PROMOTERS AND COMPOSITIONS FOR CONTAINERS AND OTHER ARTICLES SWIMC LLC (US) 2025-12-03 EP claimed
EP-4288489-B1 CROSSLINKABLE ACRYLIC-MODIFIED EPOXY COATING COMPOSITION ARKEMA INC (US) 2025-11-05 EP claimed
EP-4642645-A1 MULTILAYER COMPOSITES COMPRISING A POLYMERIC LAYER AND A CONTINUOUS FIBER REINFORCED POLYMERIC COMPOSITE Avient Corporation (US) 2025-11-05 EP claimed
US-4199361-A 3-ANILINO-5-PYRAZOLONE MAGENTA COLOR-FORMING COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1980-04-22 US claimed
US-4167540-A BUTADIENE-STYRENE COPOLYMER HOECHST AKTIENGESELLSCHAFT (DE) 1979-09-11 US claimed
US-4119592-A Rubbery bladders from epoxy compositions THE B. F. GOODRICH COMPANY (US) 1978-10-10 US claimed
US-4101398-A Process for hardening a resin which is the reaction product of an epoxy resin, an olefinically unsaturated monocarboxylic acid and a polycarboxylic acid anhydride unit HOECHST AKTIENGESELLSCHAFT (DE) 1978-07-18 US claimed
US-4097457-A Process for preparing high molecular weight polycarbonates MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1978-06-27 US claimed
US-4025578-A Elastomeric liquid polymer vulcanizates from epoxy resin, liquid carboxy terminated polymer, dihydric phenol, and an amine THE B. F. GOODRICH COMPANY (US) 1977-05-24 US claimed
US-3988386-A NOVOLAKS; BINDERS; ACID CATALYSTS HOECHST AKTIENGESELLSCHAFT (DT) 1976-10-26 US claimed
US-3965033-A Process for the production of oil-containing microcapsules FUJI PHOTO FILM CO., LTD. (JA) 1976-06-22 US claimed
US-3959404-A Powder coating compositions containing glycidyl ester copolymers and phenolic hydroxy terminated crosslinking agent FORD MOTOR COMPANY (US) 1976-05-25 US claimed
US-3952078-A Method of prilling ammonium nitrate and urea through epoxy-resin lined bores FISONS LIMITED (EN) 1976-04-20 US claimed