Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4071082 | 0.99 | MAPT (0.57) | MAPTALDH1A1HTTNPSR1CLK1 | |
| Acetic Acid SCHEMBL5577103 | 0.96 | MAPT (0.52) | MAPTALDH1A1HTTNPSR1CLK1 | |
| SCHEMBL4058629 | 0.85 | MAPT (0.43) | MAPTALDH1A1HTTNPSR1CLK1 | |
| SCHEMBL4064914 | 0.77 | MAPT (0.40) | MAPTALDH1A1HTTNPSR1CLK1 | |
| SCHEMBL4062560 | 0.72 | MAPT (0.98) | MAPTALDH1A1HTTNPSR1CLK1 | |
| Hydrochloric Acid SCHEMBL4290512 | 0.71 | MAPT (1.00) | MAPTALDH1A1HTTNPSR1CLK1 | |
| SCHEMBL4063265 | 0.66 | CLK1 (1.00) | MAPTALDH1A1HTTNPSR1CLK1 | |
| SCHEMBL30697294 | 0.66 | CLK1 (1.00) | MAPTALDH1A1HTTNPSR1CLK1 | |
| SCHEMBL4066650 | 0.65 | CLK1 (0.70) | MAPTALDH1A1HTTNPSR1CLK1 | |
| SCHEMBL4063361 | 0.65 | ALDH1A1 (0.64) | MAPTALDH1A1HTTNPSR1CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960777-B1 | SERUM-FREE EXPANSION OF CELLS IN CULTURE | CHOONGWAE PHARMA CORP (KR) | 2009-10-21 | — | — | EP | disclosed |
| US-20070128669-A1 | Serum-free expansion of cells in culture | INSTITUTE FOR CHEMICAL GENOMICS (US) | 2007-06-07 | — | — | US | disclosed |