Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4058629 | 0.92 | MAPT (0.43) | MAPTALDH1A1LMNATDP1KDM4E | |
| SCHEMBL4062563 | 0.77 | MAPT (0.55) | MAPTALDH1A1LMNATDP1KDM4E | |
| SCHEMBL4288372 | 0.76 | ALDH1A1 (0.60) | MAPTALDH1A1LMNATDP1KDM4E | |
| SCHEMBL4288368 | 0.76 | ALDH1A1 (0.60) | MAPTALDH1A1LMNATDP1KDM4E | |
| Hydrochloric Acid SCHEMBL4071082 | 0.76 | MAPT (0.57) | MAPTALDH1A1LMNATDP1KDM4E | |
| Acetic Acid SCHEMBL5577103 | 0.74 | MAPT (0.52) | MAPTALDH1A1LMNATDP1GAA | |
| SCHEMBL4288413 | 0.69 | ALDH1A1 (0.73) | MAPTALDH1A1LMNATDP1KDM4E | |
| SCHEMBL4288409 | 0.69 | ALDH1A1 (0.73) | MAPTALDH1A1LMNATDP1KDM4E | |
| SCHEMBL4066326 | 0.69 | MAPT (0.77) | MAPTALDH1A1LMNATDP1KDM4E | |
| SCHEMBL4241354 | 0.69 | ALDH1A1 (0.49) | MAPTALDH1A1LMNATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960777-B1 | SERUM-FREE EXPANSION OF CELLS IN CULTURE | CHOONGWAE PHARMA CORP (KR) | 2009-10-21 | — | — | EP | disclosed |
| US-20070128669-A1 | Serum-free expansion of cells in culture | INSTITUTE FOR CHEMICAL GENOMICS (US) | 2007-06-07 | — | — | US | disclosed |