Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 8/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.45 |
| ▸ | IKBKB | O14920 | 3/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.37 |
| ▸ | USP1 | O94782 | 2/20 | 0.37 |
| ▸ | WDR48 | Q8TAF3 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4068033 | 0.87 | MAPT (0.40) | CYP11B1CYP11B2CYP19A1IKBKBMAPT | |
| SCHEMBL13848073 | 0.86 | CYP19A1 (0.45) | CYP11B1CYP11B2CYP19A1USP1WDR48 | |
| SCHEMBL4398308 | 0.82 | CYP11B1 (0.49) | CYP11B1CYP11B2CYP19A1MAPT | |
| SCHEMBL4063295 | 0.81 | MAPT (0.46) | SMPD1MAPT | |
| SCHEMBL4067194 | 0.80 | MEN1 (0.41) | CD274CARM1 | |
| SCHEMBL4072661 | 0.80 | GSK3B (0.43) | MAPT | |
| SCHEMBL4068393 | 0.80 | CYP19A1 (0.49) | CYP19A1CD274MAPTCARM1 | |
| SCHEMBL4061183 | 0.79 | NPC1 (0.41) | PDCD1CD274 | |
| SCHEMBL4071266 | 0.79 | MAOB (0.42) | MAPT | |
| SCHEMBL13847779 | 0.78 | HSP90AA1 (0.43) | CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |