Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4072661 | 0.89 | GSK3B (0.43) | MAPTTSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL4068033 | 0.89 | MAPT (0.40) | MAPTTSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL13848290 | 0.84 | HDAC1 (0.43) | MAPTHSD17B10ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4071266 | 0.84 | MAOB (0.42) | MAPTTSHRHSD17B10ALDH1A1HPGD | |
| SCHEMBL4063115 | 0.81 | CYP11B1 (0.45) | MAPTSMPD1 | |
| SCHEMBL4065754 | 0.81 | MEN1 (0.41) | MAPTHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL4071442 | 0.80 | BRD4 (0.38) | MAPTHSD17B10HPGDLMNAMAPK1 | |
| SCHEMBL4062041 | 0.80 | MEN1 (0.43) | NPC1RAB9A | |
| SCHEMBL4067194 | 0.80 | MEN1 (0.41) | TSHRHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL4069185 | 0.79 | HSP90AA1 (0.42) | MAPTKDM4ESMN1; SMN2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |