Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 8/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.49 |
| ▸ | FNTA | P49354 | 5/20 | 0.45 |
| ▸ | FNTB | P49356 | 5/20 | 0.45 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.38 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4373611 | 0.92 | FNTA (0.46) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL13848456 | 0.89 | AGTR2 (0.44) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL4068393 | 0.85 | CYP19A1 (0.49) | CYP19A1MAPT | |
| SCHEMBL4067194 | 0.84 | MEN1 (0.41) | — | |
| SCHEMBL4068033 | 0.84 | MAPT (0.40) | CYP11B1CYP11B2CYP19A1MAPT | |
| SCHEMBL4384845 | 0.83 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP19A1AGTR2 | |
| SCHEMBL4061183 | 0.82 | NPC1 (0.41) | — | |
| SCHEMBL4063115 | 0.82 | CYP11B1 (0.45) | CYP11B1CYP11B2CYP19A1MAPT | |
| SCHEMBL13848418 | 0.80 | CYP19A1 (0.42) | CYP11B1CYP11B2CYP19A1CYP17A1AGTR2 | |
| SCHEMBL4063295 | 0.78 | MAPT (0.46) | PDE4BCYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |