SCHEMBL40632

SCHEMBL40632

[CH2]c1ccc(Cl)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28508743 0.96
SCHEMBL6606391 0.96
SCHEMBL29142535 0.96
SCHEMBL387589 0.90 CYP1A2 (0.55)
SCHEMBL6045133 0.83 GRM5 (0.47)
SCHEMBL6744390 0.83 IDO1 (0.46)
SCHEMBL2092129 0.83 MAOA (0.58)
SCHEMBL8584816 0.83 TAAR1 (0.54)
SCHEMBL6710729 0.83 MAPT (0.43)
SCHEMBL8438727 0.79 HPGD (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 23473 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
CN-118344340-A Quinolinone compound containing 1,2, 4-triazole or 1,3, 4-oxadiazole structure and preparation and application thereof 贵州大学 2024-07-16 CN claimed
CN-118344265-A Amide compound and preparation method and application thereof 河北大学 2024-07-16 CN claimed
CN-113402436-B Tertiary amino acid derivative, preparation method and application thereof 安徽农业大学 2024-07-12 CN claimed
WO-2024133200-A1 P2X3 RECEPTOR ANTAGONISTS RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA (IT) 2024-06-27 WO claimed
EP-4389746-A2 P2X3 RECEPTOR ANTAGONISTS Recordati Industria Chimica E Farmaceutica SPA (IT) 2024-06-26 EP claimed
CN-118239883-A Preparation method of lysine-specific demethylase 1 (LSD 1) inhibitor 江苏联环药业股份有限公司 2024-06-25 CN claimed
CN-118206748-A PCB electroplating additive and preparation method thereof 广东利尔化学有限公司 2024-06-18 CN claimed
CN-118184703-A Synthesis method of alpha-substituted chiral phosphonate compound 中国人民解放军军事科学院防化研究院 2024-06-14 CN claimed
EP-3849664-B1 PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE GENENTECH INC (US) 2024-06-12 EP claimed
US-3993646-A Process for the ring expansion of penicillins to cephalosporin compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-11-23 US claimed
US-3992405-A ESPECIALLY FOR DYEING POLYACRYLIC FIBERS BAYER AKTIENGESELLSCHAFT (DT) 1976-11-16 US claimed
US-3981888-A Process for preparing (1-oxo-2-phenyl, halophenyl or thienyl-2-methyl-6,7-dichloro-5-indanyloxy)acetic acid MERCK & CO., INC. (US) 1976-09-21 US claimed
US-3979390-A Butyrophenone derivatives and production thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-09-07 US claimed
US-3963714-A Quaternary ammonium salts BASF AKTIENGESELLSCHAFT (DT) 1976-06-15 US claimed
US-3960838-A Mercaptopseudodisaccharides SMITHKLINE CORPORATION (US) 1976-06-01 US claimed
US-3950408-A Process for preparing [1-oxo-2-cyclopentyl (or 2-isopropyl)-2-methyl-6,7-dichloro-5-indanyloxy] acetic acid MERCK & CO., INC. (US) 1976-04-13 US claimed
US-3947470-A CORONARY VASODILATORS, TREATMENT OF ANGINA PECTORIS SMITHKLINE CORPORATION (US) 1976-03-30 US claimed
US-3932423-A TREATMENT OF PSYCHOLOGICAL DISORDERS YOSHITOMI PHARMACEUTICAL INDUSTRIES (JA) 1976-01-13 US claimed
US-3931178-A ANTIHISTAMINES SANDOZ INC. (US) 1976-01-06 US claimed