Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4287880 | 0.71 | HTR2A (0.32) | HTR2A | |
| SCHEMBL4958308 | 0.69 | HTR2A (0.33) | HTR2A | |
| SCHEMBL19690786 | 0.68 | HTR2A (0.32) | HTR2A | |
| SCHEMBL4295979 | 0.63 | HTR2A (0.31) | HTR2A | |
| SCHEMBL6835993 | 0.63 | KDM4E (0.30) | HTR2A | |
| SCHEMBL8330852 | 0.60 | HTR2A (0.36) | HTR2A | |
| SCHEMBL10849998 | 0.59 | HTR2A (0.32) | HTR2A | |
| SCHEMBL2290547 | 0.58 | HTR2A (0.39) | HTR2A | |
| SCHEMBL8197562 | 0.58 | — | — | |
| SCHEMBL9929810 | 0.58 | HTR2A (0.32) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123971-A1 | BENZOPYRAN AND BENZOXEPIN PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2009-10-08 | — | — | WO | disclosed |