Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11884483 | 0.92 | HTR2A (0.37) | HTR2AHTR6KDM4ECYP2D6LMNA | |
| SCHEMBL6204566 | 0.83 | HTR2A (0.33) | HTR2AHTR6 | |
| SCHEMBL9806274 | 0.78 | — | — | |
| SCHEMBL3239448 | 0.74 | HTR2A (0.45) | HTR2AHTR6KDM4ECYP2D6LMNA | |
| SCHEMBL1664032 | 0.72 | HTR6 (0.32) | HTR2AHTR6 | |
| SCHEMBL6633705 | 0.71 | TBXA2R (0.36) | KDM4ETP53MEN1KMT2A | |
| SCHEMBL27817134 | 0.71 | HTR6 (0.31) | HTR2AHTR6 | |
| SCHEMBL8330852 | 0.69 | HTR2A (0.36) | HTR2AHTR6KDM4ECYP2D6LMNA | |
| SCHEMBL6195775 | 0.68 | SHBG (0.32) | — | |
| SCHEMBL28839808 | 0.68 | HTR2A (0.34) | HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11040995-B2 | Catalyst comprising a metallocene complex and co-catalyst | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2021-06-22 | — | — | US | claimed |
| US-20200270292-A1 | CATALYST COMPRISING A METALLOCENE COMPLEX AND CO-CATALYST | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-08-27 | — | — | US | claimed |
| EP-3400230-B1 | CATALYST COMPRISING A METALLOCENE COMPLEX AND A CO-CATALYST | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2019-09-11 | — | — | EP | claimed |
| EP-3400230-A1 | CATALYST COMPRISING A METALLOCENE COMPLEX AND A CO-CATALYST | SABIC Global Technologies B.V. (NL) | 2018-11-14 | — | — | EP | claimed |
| WO-2017118617-A1 | CATALYST COMPRISING A METALLOCENE COMPLEX AND A CO-CATALYST | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-07-13 | — | — | WO | claimed |
| US-7575785-B2 | use thereof in liquid-crystalline media, and and to electro-optical display elements containing these liquid-crystalline media; negative dielectric anisotropy | MERCK PATENT GMBH (DE) | 2009-08-18 | — | — | US | claimed |
| US-20060202163-A1 | Cyclopenta[a]naphthaline derivatives | MERCK PATENT GMBH (DE) | 2006-09-14 | — | — | US | claimed |
| US-20250223285-A1 | NOVEL HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS | JACOBIO PHARMACEUTICALS CO LTD (CN) | 2025-07-10 | — | — | US | disclosed |
| US-11339230-B2 | Transition metal compound, catalyst composition including the same, and method for preparing ethylene homopolymer or copolymer of ethylene and α-olefin using the same | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2022-05-24 | — | — | US | disclosed |
| US-11339230-B2 | Transition metal compound, catalyst composition including the same, and method for preparing ethylene homopolymer or copolymer of ethylene and α-olefin using the same | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2022-05-24 | — | — | US | disclosed |
| US-11040995-B2 | Catalyst comprising a metallocene complex and co-catalyst | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2021-06-22 | — | — | US | disclosed |
| US-20210139617-A1 | NOVEL TRANSITION METAL COMPOUND, CATALYST COMPOSITION INCLUDING THE SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMER OR COPOLYMER OF ETHYLENE AND ALPHA-OLEFIN USING THE SAME | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2021-05-13 | — | — | US | disclosed |
| US-20210139617-A1 | NOVEL TRANSITION METAL COMPOUND, CATALYST COMPOSITION INCLUDING THE SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMER OR COPOLYMER OF ETHYLENE AND ALPHA-OLEFIN USING THE SAME | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2021-05-13 | — | — | US | disclosed |
| US-6737125-B2 | SUCH AS 8,9-DIFLUORO-7-(4-PENTYLPHENYL)-2-PROPYL-2,3-DIHYDRO-1H -CYCLOPENTA(A)NAPHTHALENE; FOR USE IN AUTOMOBILE INTERIORS | CLARIANT FINANCE (BVI) LIMITED (VG) | 2004-05-18 | — | — | US | disclosed |
| US-6737125-B2 | SUCH AS 8,9-DIFLUORO-7-(4-PENTYLPHENYL)-2-PROPYL-2,3-DIHYDRO-1H -CYCLOPENTA(A)NAPHTHALENE; FOR USE IN AUTOMOBILE INTERIORS | CLARIANT FINANCE (BVI) LIMITED (VG) | 2004-05-18 | — | — | US | disclosed |
| US-6706707-B2 | TREATMENT OR PREVENTION OF MGLUR5 RECEPTOR MEDIATED DISORDERS. | HOFFMAN-LA ROCHE INC. | 2004-03-16 | — | — | US | disclosed |
| US-20030108684-A1 | Such as 8,9-difluoro-7-(4-pentylphenyl)-2-propyl-2,3-dihydro-1H -cyclopenta(a)naphthalene; for use in automobile interiors | CLARIANT INTERNATIONAL LTD. | 2003-06-12 | — | — | US | disclosed |
| US-20030108684-A1 | Such as 8,9-difluoro-7-(4-pentylphenyl)-2-propyl-2,3-dihydro-1H -cyclopenta(a)naphthalene; for use in automobile interiors | CLARIANT INTERNATIONAL LTD. | 2003-06-12 | — | — | US | disclosed |
| EP-1129090-A1 | PENTAAZA-CYCLOPENTA A]NAPHTHALENE DERIVATIVES AS LIGANDS FOR GABA A? $g(a)5 RECEPTORS | MERCK SHARP & DOHME LTD. (GB) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000029412-A1 | PENTAAZA-CYCLOPENTA[A]NAPHTHALENE DERIVATIVES AS LIGANDS FOR GABAA α5 RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 2000-05-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030108684-A1 | Such as 8,9-difluoro-7-(4-pentylphenyl)-2-propyl-2,3-dihydro-1H -cyclopenta(a)naphthalene; for use in automobile interiors | SCO2, CYP2F1, OGFOD1 | HTR2A 3721/4885HTR6 4492/4885KDM4E 3867/4885 |
| US-20210139617-A1 | NOVEL TRANSITION METAL COMPOUND, CATALYST COMPOSITION INCLUDING THE SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMER OR COPOLYMER OF ETHYLENE AND ALPHA-OLEFIN USING THE SAME | NOTUM, ALOX12, ETFA | HTR2A 4375/4885HTR6 4036/4885KDM4E 3020/4885 |
| US-20250223285-A1 | NOVEL HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS | PTPN5, PTPN1, PTPRJ | HTR2A 3938/4885HTR6 4326/4885KDM4E 1233/4885 |
| US-20060202163-A1 | Cyclopenta[a]naphthaline derivatives | XPA, XDH, NUCB2 | HTR2A 1814/4885HTR6 4375/4885KDM4E 4506/4885 |
| US-11339230-B2 | Transition metal compound, catalyst composition including the same, and method for preparing ethylene homopolymer or copolymer of ethylene and α-olefin using the same | NOTUM, ALOX12, ETV6 | HTR2A 4415/4885HTR6 3886/4885KDM4E 3142/4885 |
| US-11040995-B2 | Catalyst comprising a metallocene complex and co-catalyst | CCRL2, UBE2L3, MAL2 | HTR2A 3350/4885HTR6 3212/4885KDM4E 1016/4885 |
| US-20200270292-A1 | CATALYST COMPRISING A METALLOCENE COMPLEX AND CO-CATALYST | LAS1L, CCNE2, CKS2 | HTR2A 3283/4885HTR6 2843/4885KDM4E 517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.