SCHEMBL4958308

SCHEMBL4958308

NC1=CC2C(=CC=Cc3ccccc32)S1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.33
HTR6 P50406 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6835993 0.77 KDM4E (0.30) HTR2A
SCHEMBL4295561 0.71 KDM4E (0.33)
SCHEMBL4287880 0.70 HTR2A (0.32) HTR2A
SCHEMBL4063453 0.69 HTR2A (0.31) HTR2A
SCHEMBL19690786 0.63 HTR2A (0.32) HTR2A
SCHEMBL27543426 0.62 TRPA1 (0.34)
SCHEMBL4295979 0.62 HTR2A (0.31) HTR2A
SCHEMBL3239448 0.59 HTR2A (0.45) HTR2AHTR6
SCHEMBL8330852 0.59 HTR2A (0.36) HTR2AHTR6
SCHEMBL10849998 0.58 HTR2A (0.32) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7459432-B2 Modification of feeding behavior IMPERIAL COLLEGE INNOVATIONS LTD. (GB) 2008-12-02 US disclosed
EP-1585956-A2 ASSESSMENT OF NEURONS IN THE ARCUATE NUCLEUS TO SCREEN FOR AGENTS THAT MODIFY FEEDING BEHAVIOR Oregon Health and Science University (US) 2005-10-19 EP disclosed
WO-2003026591-A9 MODIFICATION OF FEEDING BEHAVIOR IMP COLLEGE INNOVATIONS LTD (GB) 2004-07-08 WO disclosed
WO-2003027637-A2 ASSESSMENT OF NEURONS IN THE ARCUATE NUCLEUS TO SCREEN FOR AGENTS THAT MODIFY FEEDING BEHAVIOR OREGON HEALTH AND SCIENCE UNIVERSITY (US) 2003-04-03 WO disclosed