Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1037995 | 0.77 | — | — | |
| SCHEMBL1695010 | 0.75 | FDPS (0.36) | MAPTLMNA | |
| SCHEMBL5077735 | 0.71 | MAPT (0.39) | MAPTCA12CA7CA14ALDH1A1 | |
| SCHEMBL1750437 | 0.71 | MAPT (0.39) | MAPTCA12CA7CA14ALDH1A1 | |
| SCHEMBL5792071 | 0.71 | MAPT (0.39) | MAPTCA12CA7CA14ALDH1A1 | |
| SCHEMBL36573 | 0.71 | MAPT (0.39) | MAPTCA12CA7CA14ALDH1A1 | |
| SCHEMBL1913173 | 0.71 | MAPT (0.37) | MAPTCA12CA7CA14ALDH1A1 | |
| Hydrochloric Acid SCHEMBL20899797 | 0.70 | MAPT (0.38) | MAPTCA12CA7CA14ALDH1A1 | |
| SCHEMBL1081819 | 0.70 | MAPT (0.38) | MAPTCA12CA7CA14ALDH1A1 | |
| SCHEMBL21056068 | 0.68 | MAPT (0.37) | MAPTCA12CA7CA14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311792-A | Phenylether derivative, preparation method thereof, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2019-02-05 | — | — | CN | disclosed |
| CN-107417564-A | Phenylate analog derivative and its preparation method and pharmaceutical composition and purposes | 中国医学科学院药物研究所 | 2017-12-01 | — | — | CN | disclosed |
| EP-3083586-A1 | NOVEL CARBOXAMIDES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS COMPRISING THEM, AND USE THEREOF FOR PRODUCING MEDICAMENTS | Bayer Pharma Aktiengesellschaft (DE) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015091426-A1 | NOVEL CARBOXAMIDES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS COMPRISING THEM, AND USE THEREOF FOR PRODUCING MEDICAMENTS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-06-25 | — | — | WO | disclosed |
| CN-104650005-A | Pinaverium bromide synthesis method | BEIJING WINSUNNY PHARMACEUTICAL CO LTD | 2015-05-27 | — | — | CN | disclosed |
| EP-1673087-A4 | ALKOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2009-04-08 | — | — | EP | disclosed |
| CN-1897948-A | Alkoxy substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES CO (US) | 2007-01-17 | — | — | CN | disclosed |
| EP-1673087-A2 | ALKOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005032484-A9 | Alkoxy substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES CO (US) | 2006-05-18 | — | — | WO | disclosed |
| WO-2005032484-A2 | ALKOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-04-14 | — | — | WO | disclosed |
| CN-1085546-A | Aminediol protease inhibitors | SQUIBB & SONS INC (US) | 1994-04-20 | — | — | CN | disclosed |