Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1037995 | 0.97 | — | — | |
| SCHEMBL4063891 | 0.75 | MAPT (0.48) | LMNAMAPT | |
| SCHEMBL4430883 | 0.72 | FDPS (0.39) | FDPSLMNAMAPTHTT | |
| SCHEMBL4670328 | 0.72 | SIGMAR1 (0.38) | — | |
| SCHEMBL20189364 | 0.69 | — | — | |
| SCHEMBL15955662 | 0.68 | DPP7 (0.38) | FDPSLMNAMAPTHTT | |
| SCHEMBL1120453 | 0.68 | LMNA (0.45) | FDPSLMNAMAPTHTT | |
| SCHEMBL22412645 | 0.68 | LMNA (0.45) | FDPSLMNAMAPTHTT | |
| SCHEMBL3132292 | 0.68 | FDPS (0.36) | FDPSLMNAMAPTHTT | |
| SCHEMBL8742797 | 0.68 | FDPS (0.36) | FDPSLMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109575044-A | 2-(camptothecine -10- oxygroup) acetamides and application | 西安交通大学 | 2019-04-05 | — | — | CN | disclosed |
| EP-3380484-A1 | NEW 6-OXA-3,9, 15-TRIAZA-BICYCLO[9.3.1 ]PENTADEC A- 1 ( 14), 1 1 ( 15), 12-TRIENE DERIVATIVES BASED COMPOUNDS AND THEIR APPLICATION AS LIGANDS OF ESSENTIAL METAL ION BASED MRI AND 52MN BASED PET CONTRAST AGENTS | Debreceni Egyetem (HU) | 2018-10-03 | — | — | EP | disclosed |
| EP-3380472-A1 | NEW 3,6,9, 15-TETRAAZA-BICYCLO [9.3.1 ]PENTADECA- 1(14), 11(15), 12-TRIENE BASED COMPOUNDS AND THEIR APPLICATION AS LIGANDS OF ESSENTIAL METAL ION BASED MRI AND 52MN BASED PET CONTRAST AGENTS | Debreceni Egyetem (HU) | 2018-10-03 | — | — | EP | disclosed |
| WO-2017089849-A1 | NEW 6-OXA-3,9, 15-TRIAZA-BICYCLO[9.3.1 ]PENTADEC A- 1 ( 14), 1 1 ( 15), 12-TRIENE DERIVATIVES BASED COMPOUNDS AND THEIR APPLICATION AS LIGANDS OF ESSENTIAL METAL ION BASED MRI AND 52MN BASED PET CONTRAST AGENTS | DEBRECENI EGYETEM (HU) | 2017-06-01 | — | — | WO | disclosed |
| WO-2017089847-A1 | NEW 3,6,9, 15-TETRAAZA-BICYCLO [9.3.1 ]PENTADECA- 1(14), 11(15), 12-TRIENE BASED COMPOUNDS AND THEIR APPLICATION AS LIGANDS OF ESSENTIAL METAL ION BASED MRI AND 52MN BASED PET CONTRAST AGENTS | DEBRECENI EGYETEM (HU) | 2017-06-01 | — | — | WO | disclosed |
| EP-2593112-A2 | NOVEL ANTIBACTERIAL COMPOUNDS, METHODS OF MAKING THEM, AND USES THEREOF | Albany Molecular Research, Inc. (US) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012006321-A2 | NOVEL ANTIBACTERIAL COMPOUNDS, METHODS OF MAKING THEM, AND USES THEREOF | ALBANY MOLECULAR RESEARCH, INC. (US) | 2012-01-12 | — | — | WO | disclosed |