SCHEMBL40640

SCHEMBL40640

CCCCCCCCCCCCCCCCCC(=O)O[C@H]1[C@H](O[C@@H]2[C@@H](C)[C@H](O[C@H]3C[C@@](C)(OC)[C@@H](O)[C@H](C)O3)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]2(C)O)O[C@H](C)C[C@@H]1N(C)C

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.87
HTR1A P08908 1/20 0.87
DRD1 P21728 1/20 0.87
SLC6A2 P23975 1/20 0.87
OPRM1 P35372 1/20 0.87
DRD3 P35462 1/20 0.87
SLC6A3 Q01959 1/20 0.87
CYP3A4 P08684 10/20 0.86
SLCO1B3 Q9NPD5 3/20 0.86
SLCO1B1 Q9Y6L6 3/20 0.86
USP2 O75604 3/20 0.86
ABCB11 O95342 2/20 0.83
MAPK1 P28482 2/20 0.83
MEN1 O00255 1/20 0.83
TP53 P04637 1/20 0.83
MAPT P10636 1/20 0.83
HPGD P15428 1/20 0.83
ALOX12 P18054 1/20 0.83
RECQL P46063 1/20 0.83
BLM P54132 1/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL788111 1.00 PGR (0.87) PGRHTR1ADRD1SLC6A2OPRM1
Erythromycin SCHEMBL8369453 0.98 PGR (0.83) PGRHTR1ADRD1SLC6A2OPRM1
Erythromycin Ethylsuccinate SCHEMBL5697690 0.95 CYP3A4 (0.89) PGRHTR1ADRD1SLC6A2OPRM1
2'-O-Acetylerythromycin A SCHEMBL149240 0.93 PGR (0.79) PGRHTR1ADRD1SLC6A2OPRM1
SCHEMBL31005471 0.93 CYP3A4 (0.90) PGRHTR1ADRD1SLC6A2OPRM1
Erythromycin Propionate SCHEMBL153012 0.93 PGR (1.00) PGRHTR1ADRD1SLC6A2OPRM1
Erythromycin Propionate SCHEMBL30382832 0.93 PGR (1.00) PGRHTR1ADRD1SLC6A2OPRM1
Erythromycin Ethylsuccinate SCHEMBL18259 0.93 CYP3A4 (1.00) PGRHTR1ADRD1SLC6A2OPRM1
Erythromycin Ethylsuccinate SCHEMBL5082211 0.93 CYP3A4 (1.00) PGRHTR1ADRD1SLC6A2OPRM1
Erythromycin Ethylsuccinate SCHEMBL537373 0.93 CYP3A4 (1.00) PGRHTR1ADRD1SLC6A2OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5123 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250228841-A1 COMPOSITIONS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES APTORUM THERAPEUTICS LTD (HK) 2025-07-17 US claimed
US-12285471-B2 Methods for treating pulmonary disease using inter-alpha inhibitor proteins PROTHERA BIOLOGICS, INC. (US) 2025-04-29 US claimed
US-12274830-B2 Nitric oxide inhalation therapy for infants with bronchiolitis BEYOND AIR LTD (IL) 2025-04-15 US claimed
US-20250099557-A1 ANTIBIOTIC PHARMACEUTICAL COMPOSITION CAPABLE OF SUBCUTANEOUS ADMINISTRATION SHANGHAI BAO PHARMACEUTICALS CO., LTD. (CN) 2025-03-27 US claimed
CN-119548460-A Erythromycin stearate nano micelle oral liquid preparation and preparation method thereof 神威药业集团有限公司 2025-03-04 CN claimed
CN-118873548-A Anti-liver cancer cell preparation and application thereof 新乡医学院 2024-11-01 CN claimed
US-20240282425-A1 AUTHENTICATION METHODS AND SYSTEMS FOR DISPENSED PRESCRIPTIONS LOW GORDON KEITH (US) 2024-08-22 US claimed
US-20240173512-A1 METHODS FOR POTENTIATING ANTIMICROBIAL AGENTS STREETERVILLE CAPITAL, LLC 2024-05-30 US claimed
EP-4374848-A1 ANTIBIOTIC PHARMACEUTICAL COMPOSITION CAPABLE OF SUBCUTANEOUS ADMINISTRATION Shanghai Bao Pharmaceuticals Co., Ltd. (CN) 2024-05-29 EP claimed
US-20240122859-A1 EXTENDED RELEASE MULTIPLE UNIT PELLET SYSTEM COMPOSITION AND ITS PROCESS FOR THE PREPARATION NOKHA TRADING LLP (IN) 2024-04-18 US claimed
EP-0277741-A1 Spherical granules having core and their production Takeda Chemical Industries, Ltd. (JP) 1988-08-10 EP claimed
EP-0109102-B1 STORAGE STABLE TOPICAL PHARMACEUTICAL COMPOSITION INCLUDING NITROGEN-CONTAINING STABILIZERS THE PROCTER & GAMBLE COMPANY (US) 1988-01-20 EP claimed
EP-0109102-A2 Storage stable topical pharmaceutical composition including nitrogen-containing stabilizers THE PROCTER & GAMBLE COMPANY (US) 1984-05-23 EP claimed
EP-0027286-B1 ANTI-ACNE COMPOSITION COMPRISING DIISOPROPYL SEBACATE THE PROCTER & GAMBLE COMPANY (US) 1984-02-08 EP claimed
US-4369172-A Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose FOREST LABORATORIES INC. (US) 1983-01-18 US claimed
US-4299826-A TOPICAL APPLICATION OF ERYTHROMYCIN OR DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 1981-11-10 US claimed
EP-0001871-B1 AN ERYTHROMYCIN COMPOUND, A PROCESS FOR PREPARING THE COMPOUND AND COMPOSITIONS CONTAINING THE COMPOUND USEFUL IN THE TREATMENT OF ACNE THE PROCTER & GAMBLE COMPANY (US) 1981-07-29 EP claimed
EP-0027286-A2 Anti-acne composition comprising diisopropyl sebacate THE PROCTER & GAMBLE COMPANY (US) 1981-04-22 EP claimed
US-4261982-A ZINC ERYTHROMYCIN FOR ACNE THE PROCTER & GAMBLE COMPANY (US) 1981-04-14 US claimed
EP-0001871-A1 An erythromycin compound, a process for preparing the compound and compositions containing the compound useful in the treatment of acne THE PROCTER & GAMBLE COMPANY (US) 1979-05-16 EP claimed