Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 13/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 13/20 | 0.53 |
| ▸ | ITGAV | P06756 | 13/20 | 0.53 |
| ▸ | ITGB6 | P18564 | 3/20 | 0.53 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.53 |
| ▸ | ITGA5 | P08648 | 9/20 | 0.53 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4919562 | 0.81 | ITGB3 (0.67) | ITGB1ITGB3ITGAVITGB6ITGB5 | |
| SCHEMBL4064183 | 0.81 | ITGB1 (0.74) | ITGB1ITGB3ITGAVITGB6ITGB5 | |
| Hydrochloric Acid SCHEMBL4071123 | 0.80 | ITGB3 (0.66) | ITGB1ITGB3ITGAVITGB6ITGB5 | |
| SCHEMBL18067805 | 0.72 | ITGB1 (0.85) | ITGB1ITGB3ITGAVITGB6ITGB5 | |
| SCHEMBL4068426 | 0.72 | ITGB1 (0.49) | ITGB1ITGB3ITGAVITGB6ITGB5 | |
| SCHEMBL18056099 | 0.72 | ITGB3 (0.77) | ITGB1ITGB3ITGAVITGB6ITGB5 | |
| SCHEMBL4066463 | 0.71 | ITGB1 (0.83) | ITGB1ITGB3ITGAVITGB6ITGB5 | |
| SCHEMBL4918910 | 0.71 | ITGB1 (0.81) | ITGB1ITGB3ITGAVITGB6ITGB5 | |
| SCHEMBL14270716 | 0.70 | ITGB1 (0.83) | ITGB1ITGB3ITGAVITGB6ITGB5 | |
| SCHEMBL4070201 | 0.70 | ITGB1 (0.79) | ITGB1ITGB3ITGAVITGB6ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049490-A1 | N-(BENZOYL)-O- [2- (PYRIDIN- 2 -YLAMINO) ETHYL]-L-TYROSINE DERIVATIVES AND RELATED COMPOUNDS AS A5B1 ANTAGONISTS FOR THE TREATMENT OF SOLID TUMORS | Astra Zeneca AB (SE) | 2009-04-22 | — | — | EP | disclosed |
| WO-2007141473-A1 | N-(BENZOYL)-O- [2- (PYRIDIN- 2 -YLAMINO) ETHYL] -L-TYROSINE DERIVATIVES AND RELATED COMPOUNDS AS A5B1 ANTAGONISTS FOR THE TREATMENT OF SOLID TUMORS | ASTRAZENECA AB (SE) | 2007-12-13 | — | — | WO | disclosed |