Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.67 |
| ▸ | ITGAV | P06756 | 13/20 | 0.67 |
| ▸ | ITGB1 | P05556 | 9/20 | 0.67 |
| ▸ | ITGB6 | P18564 | 3/20 | 0.67 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.67 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.58 |
| ▸ | MDM4 | O15151 | 1/20 | 0.56 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4071123 | 0.99 | ITGB3 (0.66) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL18056099 | 0.83 | ITGB3 (0.77) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL18077363 | 0.83 | HDAC3 (0.50) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL4064188 | 0.81 | ITGB1 (0.53) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL6177908 | 0.80 | ITGB3 (1.00) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL18056100 | 0.80 | ITGB3 (0.63) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL27598292 | 0.79 | ITGB3 (0.63) | ITGB3ITGAVITGB1ITGB6ITGB5 | |
| SCHEMBL13902119 | 0.79 | — | — | |
| SCHEMBL13902100 | 0.79 | — | — | |
| SCHEMBL14270716 | 0.79 | ITGB1 (0.83) | ITGB3ITGAVITGB1ITGB6ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080045521-A1 | PHENYLALANINE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-02-21 | — | — | US | disclosed |
| US-20080045521-A1 | PHENYLALANINE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-02-21 | — | — | US | disclosed |
| US-20080045521-A1 | PHENYLALANINE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045521-A1 | PHENYLALANINE DERIVATIVES | ITGB5, ITGB1, ITGA2B | ITGB3 6/4885ITGAV 17/4885ITGB1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.