Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IFNAR1 | P17181 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4067362 | 0.85 | IFNAR1 (0.50) | IFNAR1MAPTSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4068277 | 0.84 | IFNAR1 (0.61) | IFNAR1MAPTSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4059351 | 0.78 | IFNAR1 (0.45) | IFNAR1MAPTSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL1399195 | 0.76 | IDO1 (0.51) | IFNAR1MAPTHTR2APKMLMNA | |
| SCHEMBL1399251 | 0.75 | GPR84 (0.42) | IFNAR1MAPTLMNARECQLSMN1; SMN2 | |
| SCHEMBL4065047 | 0.75 | MAOB (0.45) | MAPTSLC6A4SLC6A2SLC6A3PKM | |
| SCHEMBL4060162 | 0.74 | RECQL (0.54) | IFNAR1MAPTSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5482488 | 0.73 | CYP2A6 (0.63) | MAPTSLC6A4KCNH2HTR2ACYP2A6 | |
| SCHEMBL4060852 | 0.73 | IFNAR1 (0.51) | IFNAR1MAPTSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4063491 | 0.73 | IFNAR1 (0.51) | IFNAR1MAPTSLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534791-B2 | Benzo[b]furane and benzo[b]thiophene derivatives | H. LUNDBECK A/S (DK) | 2009-05-19 | — | — | US | claimed |
| EP-1893596-A2 | BENZOÝB¨FURANE AND BENZOÝB¨THIOPHENE DERIVATIVES | H.Lundbeck A/S (DK) | 2008-03-05 | — | — | EP | claimed |
| WO-2007023395-A2 | BENZO[B]FURANE AND BENZO[B]THIOPHENE DERIVATIVES | H. LUNDBECK A/S (US) | 2007-03-01 | — | — | WO | claimed |
| US-20060287386-A1 | Benzo[b]furane and benzo[b]thiophene derivatives | H. LUNDBECK A/S (DK) | 2006-12-21 | — | — | US | claimed |
| US-20090192213-A1 | Benzo[b]furane And Benzo[b]thiophene Derivatives | H. LUNDBECK A/S (DK) | 2009-07-30 | — | — | US | disclosed |
| US-7534791-B2 | Benzo[b]furane and benzo[b]thiophene derivatives | H. LUNDBECK A/S (DK) | 2009-05-19 | — | — | US | disclosed |
| EP-1893596-A2 | BENZOÝB¨FURANE AND BENZOÝB¨THIOPHENE DERIVATIVES | H.Lundbeck A/S (DK) | 2008-03-05 | — | — | EP | disclosed |
| WO-2007023395-A2 | BENZO[B]FURANE AND BENZO[B]THIOPHENE DERIVATIVES | H. LUNDBECK A/S (US) | 2007-03-01 | — | — | WO | disclosed |
| US-20060287386-A1 | Benzo[b]furane and benzo[b]thiophene derivatives | H. LUNDBECK A/S (DK) | 2006-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287386-A1 | Benzo[b]furane and benzo[b]thiophene derivatives | CYP1B1, TBCB, CYP4B1 | IFNAR1 2680/4885MAPT 3465/4885SLC6A4 692/4885 |
| US-20090192213-A1 | Benzo[b]furane And Benzo[b]thiophene Derivatives | CYP1B1, TBCB, CYP4B1 | IFNAR1 2680/4885MAPT 3465/4885SLC6A4 692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.