Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | RAF1 | P04049 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064663 | 1.00 | VCAM1 (0.72) | VCAM1ALDH1A1MEN1KMT2AKDM4E | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL6101 | 0.86 | VCAM1 (0.77) | VCAM1ALDH1A1MEN1KMT2AKDM4E | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL30234086 | 0.86 | VCAM1 (0.77) | VCAM1ALDH1A1MEN1KMT2AKDM4E | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL8028245 | 0.84 | VCAM1 (0.74) | VCAM1ALDH1A1MEN1KMT2AKDM4E | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL10608939 | 0.84 | VCAM1 (0.74) | VCAM1ALDH1A1MEN1KMT2AKDM4E | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL28165768 | 0.84 | VCAM1 (0.74) | VCAM1ALDH1A1MEN1KMT2AKDM4E | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL10608947 | 0.84 | VCAM1 (0.74) | VCAM1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL1258621 | 0.84 | VCAM1 (1.00) | VCAM1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8625340 | 0.82 | VCAM1 (0.96) | VCAM1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL922714 | 0.82 | VCAM1 (0.77) | VCAM1ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1666473-B1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2013-01-02 | — | — | EP | disclosed |
| US-7601712-B2 | Such as (1)-2-(4-chloro-3-((2-chloro-4-(((2S)-4-methyl-3,4-dihydro-2H-1,4-benzoxazin-2-ly)methoxy)benzoyl)amino)phenyl)-2-methylpropanoic acid; prostaglandin receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-10-13 | — | — | US | disclosed |
| US-20070004716-A1 | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004716-A1 | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | GPR17, CYSLTR1, KIT | VCAM1 94/4885ALDH1A1 368/4885MEN1 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.