4-Chloro-3-Nitrobenzoic Acid

4-Chloro-3-Nitrobenzoic Acid

SCHEMBL6101

O=C(O)c1ccc(Cl)c([N+](=O)[O-])c1

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 2/20 0.77
CASP6 P55212 1/20 0.70
MEN1 O00255 3/20 0.68
KMT2A Q03164 3/20 0.68
ALDH1A1 P00352 3/20 0.68
KDM4E B2RXH2 1/20 0.68
TSHR P16473 3/20 0.64
LMNA P02545 2/20 0.64
MAPT P10636 2/20 0.59
RAF1 P04049 1/20 0.59
HPGD P15428 1/20 0.59
MAPK1 P28482 1/20 0.59
GFER P55789 1/20 0.59
PAX8 Q06710 1/20 0.59
HCAR3 P49019 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Chloro-3-Nitrobenzoic Acid SCHEMBL30234086 1.00 VCAM1 (0.77) VCAM1CASP6MEN1KMT2AALDH1A1
4-Chloro-3-Nitrobenzoic Acid SCHEMBL10608947 0.98 VCAM1 (0.74) VCAM1CASP6MEN1KMT2AALDH1A1
4-Chloro-3-Nitrobenzoic Acid SCHEMBL28165768 0.98 VCAM1 (0.74) VCAM1CASP6MEN1KMT2AALDH1A1
4-Chloro-3-Nitrobenzoic Acid SCHEMBL10608939 0.98 VCAM1 (0.74) VCAM1CASP6MEN1KMT2AALDH1A1
4-Chloro-3-Nitrobenzoic Acid SCHEMBL8028245 0.98 VCAM1 (0.74) VCAM1CASP6MEN1KMT2AALDH1A1
4-Chloro-3-Nitrobenzoic Acid SCHEMBL8743988 0.91 VCAM1 (0.64) VCAM1CASP6MEN1KMT2AALDH1A1
SCHEMBL1258621 0.87 VCAM1 (1.00) VCAM1MEN1KMT2AALDH1A1KDM4E
SCHEMBL4064668 0.86 VCAM1 (0.72) VCAM1CASP6MEN1KMT2AALDH1A1
SCHEMBL4064663 0.86 VCAM1 (0.72) VCAM1CASP6MEN1KMT2AALDH1A1
SCHEMBL360051 0.85 CASP6 (0.70) VCAM1CASP6MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116338060-B Determination method of genotoxic impurities in chemical bulk drug containing amino 成都硕德药业有限公司 2025-06-03 CN claimed
WO-2025087033-A1 COMPOUND CONTAINING (1,3,4-THIADIAZOLE)BENZENE-1,2-ETHYLENEDIAMINE, PREPARATION METHOD THEREFOR AND USE THEREOF 中国海洋大学 2025-05-01 WO claimed
CN-119793527-A Regeneration method of metal modified mordenite catalyst for methanol amination reaction 湖北三峡实验室 2025-04-11 CN claimed
CN-111465699-B Method for producing amines from carbonyl compounds by transaminase reaction under salt precipitation 恩齐米克斯公司 2024-09-20 CN claimed
US-12018303-B2 Method for preparing amines from carbonyl compounds by transaminase reaction under salt precipitation ENZYMICALS AG (DE) 2024-06-25 US claimed
CN-117567390-A Benzene-1, 2-ethylenediamine compound containing (1, 3, 4-thiadiazole) and preparation method and application thereof 中国海洋大学 2024-02-20 CN claimed
CN-114195644-B Process and device for selectively nitrifying p-chlorobenzoic acid 浙江工业大学 2023-11-14 CN claimed
CN-116947732-A Synthesis method of Nidaminib intermediate 江苏阿尔法药业股份有限公司 2023-10-27 CN claimed
CN-116730855-B Synthesis method of 3-amino-4-hexadecyl chlorobenzoate 苏州开元民生科技股份有限公司 2023-10-20 CN claimed
CN-116730855-A Synthesis method of 3-amino-4-hexadecyl chlorobenzoate 苏州开元民生科技股份有限公司 2023-09-12 CN claimed
EP-0751768-A1 ANTI-VIRAL AND ANTI-CANCER AGENTS RADOPATH LIMITED (GB) 1997-01-08 EP claimed
WO-1996029067-A1 ANTI-VIRAL AND ANTI-CANCER AGENTS RADOPATH LIMITED (GB) 1996-09-26 WO claimed
EP-0677292-A1 Anti-viral and anti-cancer agents RADOPATH LIMITED (GB) 1995-10-18 EP claimed
WO-1995024897-A1 ANTI-VIRAL AND ANTI-CANCER AGENTS RADOPATH LIMITED (GB) 1995-09-21 WO claimed
US-5277790-A Non-cyanide electroplating solution for gold or alloys thereof TECHNIC INCORPORATED (US) 1994-01-11 US claimed
EP-0519971-A1 NOVEL PHARMACEUTICALLY ACTIVE COMPOUNDS WHICH CAN BE FORMED FROM 1,3,4,6,7,8-HEXAHYDRO-2H-PYRIMIDO-(1,2-a)-PYRIMIDINE. EEC PHARMA SA (FR) 1992-12-30 EP claimed
WO-1991013886-A1 NOVEL PHARMACEUTICALLY ACTIVE COMPOUNDS WHICH CAN BE FORMED FROM 1,3,4,6,7,8-HEXAHYDRO-2H-PYRIMIDO-(1,2-a)-PYRIMIDINE EEC-PHARMA S.A. (FR) 1991-09-19 WO claimed
US-4421694-A Process for the preparation of nitroanilines BAYER AKTIENGESELLSCHAFT (DE) 1983-12-20 US claimed
US-4152160-A PHOTOTHERMOGRAPHY, SILVER BEHENATE FUJI PHOTO FILM CO., LTD. (JP) 1979-05-01 US claimed
US-3997342-A Photoconductive element exhibiting persistent conductivity EASTMAN KODAK COMPANY (US) 1976-12-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12018303-B2 Method for preparing amines from carbonyl compounds by transaminase reaction under salt precipitation GOT1, GOT2, OAT VCAM1 4412/4885CASP6 2918/4885MEN1 2979/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.