Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060953 | 0.86 | MEN1 (0.61) | HTTGAAGFERPLA2G2AHPGD | |
| SCHEMBL2002870 | 0.79 | PLA2G2A (0.82) | GAAPLA2G2AKDM4EMAPTCYP1A2 | |
| SCHEMBL5814525 | 0.78 | PTGS1 (0.71) | HTTGAAGFERHPGDKDM4E | |
| SCHEMBL2002582 | 0.76 | PLA2G2A (0.63) | GAAPLA2G2AKDM4EMAPTPKM | |
| SCHEMBL4070593 | 0.76 | HTT (0.52) | HTTGAAPLA2G2AHPGDKDM4E | |
| SCHEMBL2006271 | 0.75 | PLA2G2A (0.72) | GAAPLA2G2AKDM4EMAPTCYP1A2 | |
| SCHEMBL2003130 | 0.74 | PLA2G2A (0.71) | GAAPLA2G2AKDM4EMAPTCYP1A2 | |
| SCHEMBL4067480 | 0.74 | KMT2A (0.47) | HTTGAAHPGDKDM4EMAPT | |
| SCHEMBL4058640 | 0.74 | HTT (0.50) | HTTGAAHPGDKDM4EMAPT | |
| SCHEMBL4063193 | 0.74 | KMT2A (0.47) | HTTGAAPLA2G2AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960777-B1 | SERUM-FREE EXPANSION OF CELLS IN CULTURE | CHOONGWAE PHARMA CORP (KR) | 2009-10-21 | — | — | EP | disclosed |
| WO-2007062243-A9 | SERUM-FREE EXPANSION OF CELLS IN CULTURE | CHOONGWAE PHARMA CORP (KR) | 2008-12-04 | — | — | WO | disclosed |
| EP-1960777-A2 | SERUM-FREE EXPANSION OF CELLS IN CULTURE | Choongwae Pharma Corporation (KR) | 2008-08-27 | — | — | EP | disclosed |
| US-20070128669-A1 | Serum-free expansion of cells in culture | INSTITUTE FOR CHEMICAL GENOMICS (US) | 2007-06-07 | — | — | US | disclosed |
| WO-2007062243-A2 | SERUM-FREE EXPANSION OF CELLS IN CULTURE | CHOONGWAE PHARMA CORPORATION (KR) | 2007-05-31 | — | — | WO | disclosed |