Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.71 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.71 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23898354 | 0.84 | PTGS1 (0.55) | PTGS1PTGS2AKR1C3AKR1C2MAPT | |
| SCHEMBL10943893 | 0.84 | AKR1C3 (0.72) | PTGS1PTGS2AKR1C3AKR1C2MAPT | |
| SCHEMBL2996680 | 0.83 | PTGS1 (1.00) | PTGS1PTGS2AKR1C3AKR1C2MAPT | |
| SCHEMBL6025562 | 0.81 | MAPT (0.73) | PTGS1PTGS2MAPTKDM4ECYP1A2 | |
| SCHEMBL23898353 | 0.80 | PTGS1 (0.52) | PTGS1PTGS2AKR1C3AKR1C2MAPT | |
| SCHEMBL6025989 | 0.79 | PTGDR2 (0.78) | PTGS1PTGS2AKR1C3AKR1C2MAPT | |
| SCHEMBL27773537 | 0.79 | AKR1C3 (0.61) | PTGS1PTGS2AKR1C3AKR1C2MAPT | |
| SCHEMBL4064889 | 0.78 | HTT (0.57) | PTGS1PTGS2MAPTKDM4ECYP1A2 | |
| SCHEMBL5797653 | 0.78 | PTGS1 (0.74) | PTGS1PTGS2AKR1C3AKR1C2MAPT | |
| SCHEMBL28785169 | 0.78 | ABCB1 (0.58) | PTGS1PTGS2AKR1C3AKR1C2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | IRONWOOD PHARMACEUTICALS, INC. | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | FAAH2, FAAH, PTGES2 | PTGS1 7/4885PTGS2 4/4885AKR1C3 577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.