Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 3/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634028 | 0.85 | LMNA (0.60) | LMNAL3MBTL1CYP1A2PTGS1SLC6A2 | |
| SCHEMBL6616547 | 0.82 | LMNA (0.56) | LMNAL3MBTL1CYP1A2PTGS1SLC6A2 | |
| SCHEMBL7288111 | 0.82 | LMNA (0.56) | LMNAL3MBTL1CYP1A2PTGS1SLC6A2 | |
| SCHEMBL9451329 | 0.82 | LMNA (0.61) | LMNAL3MBTL1CYP1A2PTGS1SLC6A2 | |
| SCHEMBL11579600 | 0.82 | MAOB (0.59) | LMNAL3MBTL1CYP1A2PTGS1SLC6A2 | |
| SCHEMBL27367676 | 0.80 | LMNA (0.82) | LMNAL3MBTL1CYP1A2PTGS1SLC6A2 | |
| SCHEMBL339813 | 0.80 | LMNA (0.82) | LMNAL3MBTL1CYP1A2PTGS1SLC6A2 | |
| SCHEMBL27378584 | 0.80 | PPARG (0.56) | LMNAL3MBTL1CYP1A2PTGS1SLC6A2 | |
| SCHEMBL6617980 | 0.80 | RAB9A (0.49) | LMNAL3MBTL1HDAC6MAOBRAB9A | |
| SCHEMBL9406682 | 0.79 | LMNA (0.58) | LMNAL3MBTL1CYP1A2PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051964-A2 | FATTY ACID AMIDE HYDROLASE INHIBITORS | University of Connecticut (US) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008013963-A2 | FATTY ACID AMIDE HYDROLASE INHIBITORS | UNIVERSITY OF CONNECTICUT (US) | 2008-01-31 | — | — | WO | disclosed |