Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4213470 | 0.87 | EGLN1 (0.49) | EGLN1ALDH1A3METTL3 | |
| SCHEMBL2127666 | 0.80 | NPC1 (0.62) | ALDH1A1KDM4ENPC1MAPTTHRB | |
| SCHEMBL2085892 | 0.78 | RAB9A (0.50) | EGLN1ALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL2085894 | 0.78 | ALDH1A1 (0.64) | EGLN1ALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL2126827 | 0.78 | ALDH1A1 (0.65) | ALDH1A1KDM4ENPC1MAPTTHRB | |
| Hydrochloric Acid SCHEMBL2086035 | 0.77 | RAB9A (0.49) | EGLN1ALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL16686943 | 0.76 | PIK3CG (0.45) | EGLN1ALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL2087833 | 0.76 | PTGS1 (0.45) | EGLN1ALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL2087968 | 0.76 | PTGS1 (0.51) | EGLN1ALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL2086685 | 0.75 | EGLN1 (0.44) | EGLN1ALDH1A1KDM4ENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2040703-B1 | DERIVATIVES OF 2-BENZOYL-IMIDAZOPYRIDINES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2009-10-21 | — | — | EP | claimed |