SCHEMBL4065890

SCHEMBL4065890

CCC1=Cc2c(-c3cccc4ccccc34)cccc2C1[Zr](Cl)Cl

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.32
SLC6A4 P31645 6/20 0.32
DRD2 P14416 1/20 0.32
CNR1 P21554 2/20 0.31
SLC6A2 P23975 2/20 0.31
SLC6A3 Q01959 2/20 0.31
CYP2D6 P10635 1/20 0.31
KDM4E B2RXH2 3/20 0.30
CYP11B2 P19099 1/20 0.30
TDP2 O95551 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
ALOX12 P18054 1/20 0.30
MAPK1 P28482 1/20 0.30
CASP3 P42574 1/20 0.30
HTT P42858 1/20 0.30
GALK1 P51570 1/20 0.30
BLM P54132 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7627579 0.91 SLC6A4 (0.33) HTR7SLC6A4DRD2CNR1SLC6A2
SCHEMBL27541344 0.89 ALDH1A1 (0.34) ALDH1A1HPGDMAPK1L3MBTL1
SCHEMBL5688274 0.89 CNR1 (0.36) HTR7SLC6A4DRD2CNR1ALOX15
SCHEMBL27492404 0.88 CNR1 (0.40) HTR7SLC6A4DRD2CNR1SLC6A2
SCHEMBL27594164 0.87 CNR1 (0.41) HTR7SLC6A4DRD2CNR1SLC6A2
SCHEMBL27491322 0.86 NPC1 (0.32) CNR1MAPTPTPN1CNR2
SCHEMBL27491684 0.86 CES1 (0.33) HTR7
SCHEMBL27510937 0.86 CCR4 (0.30)
SCHEMBL27510574 0.86 HSD11B1 (0.32) KDM4E
SCHEMBL28576605 0.85 HPRT1 (0.33) SLC6A4DRD2CNR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7618912-B2 Preparation of supported catalyst systems BASELL POLYOLEFINE GMBH (DE) 2009-11-17 US claimed
US-7205363-B2 Using fluorided silica supported metallocene catalyst system and antistatic agent selected from polysulfone copolymer, polyamine, oil soluble sulfonic acid or mixture, for homo or copolymerization of propylene EXXON MOBIL CHEMICAL PATENTS INC. (US) 2007-04-17 US claimed
US-20040254316-A1 Polymerization processes using antistatic agents EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-16 US claimed
US-6667272-B2 Metallocene, an activator and a fluorided support; use as alpha-olefin polymerization catalysts, polypropylene EXXONMOBIL CHEMICAL PATENTS INC. 2003-12-23 US claimed
US-6664348-B2 Metallocene catalyst such as dimethylsilandiylbis(2-ethyl-4-phenyl-1-indenyl)zirconium dimethyl for polymerization of propylene EXXONMOBIL CHEMICAL PATENTS INC. 2003-12-16 US claimed
US-6524988-B2 Metallocene, an activator and a fluorided support; polymerization catalyst EXXONMOBIL CHEMICAL PATENTS INC. 2003-02-25 US claimed
US-20020160914-A1 Highly active supported catalyst compositions EXXONMOBIL CHEMICAL PATENTS INC. 2002-10-31 US claimed
US-20010051698-A1 Highly active supported catalyst compositions EXXONMOBIL CHEMICAL PATENTS INC. 2001-12-13 US claimed
US-7521507-B2 Polypropylene-based adhesive compositions EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-04-21 US disclosed
EP-2045304-A2 Polypropylene-Based Adhesive Compositions ExxonMobil Chemical Patents Inc. (US) 2009-04-08 EP disclosed
EP-1311593-B1 POLYPROPYLENE FILMS EXXONMOBIL CHEM PATENTS INC (US) 2009-01-07 EP disclosed
US-7205363-B2 Using fluorided silica supported metallocene catalyst system and antistatic agent selected from polysulfone copolymer, polyamine, oil soluble sulfonic acid or mixture, for homo or copolymerization of propylene EXXON MOBIL CHEMICAL PATENTS INC. (US) 2007-04-17 US disclosed
EP-1315858-B1 POLYPROPYLENE FIBERS AND FABRICS EXXONMOBIL CHEM PATENTS INC (US) 2007-02-07 EP disclosed
EP-1734061-A2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer and uses thereof MITSUI CHEMICALS, INC. (JP) 2006-12-20 EP disclosed
US-20010051698-A1 Highly active supported catalyst compositions EXXONMOBIL CHEMICAL PATENTS INC. 2001-12-13 US disclosed
US-20010049331-A1 SUPPORTED ORGANOMETALLIC CATALYSTS AND THEIR USE IN OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. 2001-12-06 US disclosed
WO-2001036499-A1 PREPARATION OF SUPPORTED POLYMERIZATION CATALYSTS EXXON CHEMICAL PATENTS INC. (US) 2001-05-25 WO disclosed
CN-1246871-A Propylene polymers incorporating polyethylene macromers EXXON CHEMICAL PATENTS INC (US) 2000-03-08 CN disclosed
CN-1224026-A Catalyst component for polymerizing ethylenically unsaturated monomers, catalyst and method of use thereof MITSUI CHEMICALS INC (JP) 1999-07-28 CN disclosed
CN-1160055-A Process for reducing by-product in product mixture HOECHST AG (DE) 1997-09-24 CN disclosed