SCHEMBL406610

SCHEMBL406610

CCCCCc1[c]cccc1CCCCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.46
ALOX5 P09917 2/20 0.41
PTGS2 P35354 1/20 0.41
KCNH2 Q12809 2/20 0.40
BID P55957 3/20 0.39
MCL1 Q07820 3/20 0.39
BCL2L1 Q07817 2/20 0.39
BAK1 Q16611 2/20 0.39
KAT8 Q9H7Z6 2/20 0.39
PPARA Q07869 2/20 0.39
PPARG P37231 1/20 0.39
EP300 Q09472 1/20 0.39
KAT2A Q92830 1/20 0.39
KAT2B Q92831 1/20 0.39
KAT5 Q92993 1/20 0.39
SAE1 Q9UBE0 1/20 0.39
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
TYR P14679 2/20 0.37
MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21523363 0.98 LIPG (0.49) LIPGALOX5PTGS2KCNH2BID
SCHEMBL21523337 0.98 LIPG (0.49) LIPGALOX5PTGS2KCNH2BID
SCHEMBL21523356 0.98 LIPG (0.49) LIPGALOX5PTGS2KCNH2BID
SCHEMBL21523328 0.98 LIPG (0.49) LIPGALOX5PTGS2KCNH2BID
SCHEMBL21523321 0.98 LIPG (0.49) LIPGALOX5PTGS2KCNH2BID
SCHEMBL21523320 0.98 LIPG (0.49) LIPGALOX5PTGS2KCNH2BID
SCHEMBL21523344 0.98 LIPG (0.49) LIPGALOX5PTGS2KCNH2BID
SCHEMBL21523330 0.98 LIPG (0.49) LIPGALOX5PTGS2KCNH2BID
SCHEMBL21523355 0.98 LIPG (0.49) LIPGALOX5PTGS2KCNH2BID
SCHEMBL21523332 0.98 LIPG (0.49) LIPGALOX5PTGS2KCNH2BID

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023239572-A1 ENHANCED SPECIFICITY MASS TAG DNA ADDUCTOMICS NORTHEASTERN UNIVERSITY (US) 2023-12-14 WO claimed
CN-110818545-B Method for preparing substituted aryl ketone by ketone arylation 上海化工研究院有限公司 2022-12-09 CN claimed
US-20220393118-A1 TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF CHE, CHI MING (CN) 2022-12-08 US claimed
EP-4017936-A1 TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF Che, Chi Ming (HK) 2022-06-29 EP claimed
CN-107963982-B Polyisocyanate composition and isocyanate polymer composition 旭化成株式会社 2021-11-12 CN claimed
WO-2021036978-A1 TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF CHE CHI MING (CN) 2021-03-04 WO claimed
CN-112409243-A Tetradentate ligand, gold (III) complex, and preparation method and application thereof 支志明 2021-02-26 CN claimed
CN-110818545-A Method for preparing substituted aryl ketone by ketone arylation 上海化工研究院有限公司 2020-02-21 CN claimed
US-8008385-B2 Solid alkylaryl phosphite compositions and methods for manufacturing same CHEMTURA CORPORATION (US) 2011-08-30 US claimed
EP-1831205-A1 CARBONYL-FUNCTIONALIZED THIOPHENE COMPOUNDS AND RELATED DEVICE STRUCTURES Northwestern University (US) 2007-09-12 EP claimed
WO-2007050049-A1 CARBONYL-FUNCTIONALIZED THIOPHENE COMPOUNDS AND RELATED DEVICE STRUCTURES NORTHWESTERN UNIVERSITY (US) 2007-05-03 WO claimed
US-20060186401-A1 Carbonyl-functionalized thiophene compounds and related device structures POLYERA CORPORATION 2006-08-24 US claimed
EP-0802920-B1 ANTIFUNGAL FUSACANDINS ABBOTT LAB (US) 2001-10-04 EP claimed
WO-1999016777-A1 ANTIFUNGAL CORYNECANDIN ABBOTT LABORATORIES (US) 1999-04-08 WO claimed
US-5863773-A GLYCOLIPID FUNGICIDES ABBOTT LABORATORIES (US) 1999-01-26 US claimed
US-5773421-A Antifungal fusacandins ABBOTT LABORATORIES (US) 1998-06-30 US claimed
CN-118302407-A Carbonyl compound, method for producing isocyanate compound, and isocyanate composition 旭化成株式会社 2024-07-05 CN disclosed
CN-118215651-A Method for producing isocyanate compound, method for producing urethane compound, method for recovering amine compound, and isocyanate composition 旭化成株式会社 2024-06-18 CN disclosed
US-3955027-A FLUOROCARBON POLYMERS, EXTENDERS THE DOW CHEMICAL COMPANY (US) 1976-05-04 US disclosed
US-3933669-A PHOSPHATE ESTER, HYDROGENATED QUATERPHENYLS MONSANTO COMPANY (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220393118-A1 TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF PDCD2L, TTL, TTLL12 LIPG 3854/4885ALOX5 2663/4885PTGS2 4514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.