Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP8B1 | Q9UNU6 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4067892 | 0.83 | KCNH2 (0.35) | CYP8B1KCNH2 | |
| Hydrochloric Acid SCHEMBL5798571 | 0.83 | KCNH2 (0.35) | CYP8B1KCNH2 | |
| SCHEMBL5905795 | 0.81 | MEN1 (0.37) | MAPK1CYP8B1KCNH2 | |
| SCHEMBL4063098 | 0.75 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL17060472 | 0.75 | PARP1 (0.45) | CYP8B1KCNH2 | |
| Hydrochloric Acid SCHEMBL4065017 | 0.75 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL4070008 | 0.74 | KCNH2 (0.44) | CYP8B1KCNH2 | |
| SCHEMBL5752149 | 0.74 | CYP8B1 (0.47) | CYP8B1KCNH2SLC2A1 | |
| SCHEMBL2946390 | 0.73 | KCNH2 (0.40) | CYP8B1KCNH2SLC2A1 | |
| SCHEMBL1224945 | 0.71 | CHRNB2 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1605938-B1 | Antibacterial derivatives of napthydrin and quinoline | GLAXO GROUP LTD (GB) | 2009-02-11 | — | — | EP | disclosed |
| EP-1605938-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2006-11-22 | — | — | EP | disclosed |
| EP-1605938-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004087145-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |