Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 11/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.61 |
| ▸ | ACP1 | P24666 | 4/20 | 0.41 |
| ▸ | NPY1R | P25929 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4059525 | 0.97 | HTR3A (0.61) | HTR3AHRH3ACP1NPY1R | |
| SCHEMBL4059363 | 0.82 | HTR3A (0.59) | HTR3AHRH3ACP1NPY1R | |
| SCHEMBL4057349 | 0.80 | HTR3A (0.58) | HTR3AHRH3NPY1R | |
| SCHEMBL3617516 | 0.79 | HTR3A (0.72) | HTR3AHRH3 | |
| SCHEMBL1375890 | 0.77 | HTR3A (1.00) | HTR3AHRH3 | |
| SCHEMBL1376391 | 0.77 | HTR3A (1.00) | HTR3AHRH3 | |
| SCHEMBL1376832 | 0.76 | HTR3A (1.00) | HTR3AHRH3 | |
| SCHEMBL1372483 | 0.76 | HTR3A (1.00) | HTR3AHRH3 | |
| SCHEMBL1372486 | 0.76 | HTR3A (1.00) | HTR3AHRH3 | |
| SCHEMBL28770567 | 0.74 | CYP3A4 (0.49) | HRH3ACP1NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069312-A2 | PYRIDIZINONE DERIVATIVES | Cephalon, Inc. (US) | 2009-06-17 | — | — | EP | claimed |
| WO-2008013838-A2 | PYRIDIZINONE DERIVATIVES | CEPHALON, INC. (US) | 2008-01-31 | — | — | WO | claimed |
| EP-2069312-A2 | PYRIDIZINONE DERIVATIVES | Cephalon, Inc. (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008013838-A2 | PYRIDIZINONE DERIVATIVES | CEPHALON, INC. (US) | 2008-01-31 | — | — | WO | disclosed |