Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3
The experimentally established mechanism targets of Racepinephrine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 8/20 | 0.97 |
| ▸ | ADRB1 known ✓ | P08588 | 6/20 | 0.77 |
| ▸ | ADRB3 known ✓ | P13945 | 4/20 | 0.77 |
| ▸ | ADRA2A known ✓ | P08913 | 3/20 | 0.77 |
| ▸ | ADRA2B known ✓ | P18089 | 3/20 | 0.77 |
| ▸ | ADRA2C known ✓ | P18825 | 3/20 | 0.77 |
| ▸ | ADRA1D known ✓ | P25100 | 3/20 | 0.77 |
| ▸ | ADRA1A known ✓ | P35348 | 2/20 | 0.77 |
| ▸ | ADRA1B known ✓ | P35368 | 2/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.97 |
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.97 |
| ▸ | MAPT | P10636 | 9/20 | 0.97 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.97 |
| ▸ | BLM | P54132 | 7/20 | 0.97 |
| ▸ | TSHR | P16473 | 6/20 | 0.97 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.97 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.97 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.97 |
| ▸ | GAA | P10253 | 3/20 | 0.97 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.97 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Epinephrine SCHEMBL28412215 | 1.00 | KDM4E (0.97) | KDM4ETDP1MAPTADRB2HSD17B10 | |
| Racepinephrine SCHEMBL4406973 | 0.98 | KDM4E (1.00) | KDM4ETDP1MAPTADRB2HSD17B10 | |
| Racepinephrine SCHEMBL29587492 | 0.98 | KDM4E (1.00) | KDM4ETDP1MAPTADRB2HSD17B10 | |
| L-Adrenaline SCHEMBL26986346 | 0.98 | KDM4E (1.00) | KDM4ETDP1MAPTADRB2HSD17B10 | |
| Epinephrine SCHEMBL40741 | 0.98 | KDM4E (1.00) | KDM4ETDP1MAPTADRB2HSD17B10 | |
| Epinephrine SCHEMBL29457688 | 0.98 | KDM4E (1.00) | KDM4ETDP1MAPTADRB2HSD17B10 | |
| Epinephrine SCHEMBL27968525 | 0.98 | KDM4E (1.00) | KDM4ETDP1MAPTADRB2HSD17B10 | |
| Racepinephrine SCHEMBL40742 | 0.98 | KDM4E (1.00) | KDM4ETDP1MAPTADRB2HSD17B10 | |
| L-Adrenaline SCHEMBL20608410 | 0.98 | KDM4E (1.00) | KDM4ETDP1MAPTADRB2HSD17B10 | |
| Epinephrine SCHEMBL7394380 | 0.90 | KDM4E (0.83) | KDM4ETDP1MAPTADRB2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008116165-A9 | METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION | NEXT SAFETY INC (US) | 2009-06-11 | — | — | WO | claimed |
| WO-2008116165-A2 | METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION | NEXT SAFETY, INC. (US) | 2008-09-25 | — | — | WO | claimed |
| US-20080066741-A1 | METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION | HUNTER, CHARLES ERIC | 2008-03-20 | — | — | US | claimed |
| US-20240123168-A1 | PRODUCT DELIVERY DEVICES AND METHODS | MUSTAPHA JIHAD A (US) | 2024-04-18 | — | — | US | disclosed |
| EP-4255541-A1 | PRODUCT DELIVERY DEVICES AND METHODS | Breathe Restore, Inc. (US) | 2023-10-11 | — | — | EP | disclosed |
| US-20230181847-A1 | PRODUCT DELIVERY DEVICES AND METHODS | BREATHE RESTORE INC (US) | 2023-06-15 | — | — | US | disclosed |
| US-11672929-B2 | Product delivery devices and methods | BREATHE RESTORE, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| WO-2022118225-A1 | PRODUCT DELIVERY DEVICES AND METHODS | BREATHE RESTORE, INC. (US) | 2022-06-09 | — | — | WO | disclosed |
| US-20220168516-A1 | PRODUCT DELIVERY DEVICES AND METHODS | BREATHE RESTORE, INC. | 2022-06-02 | — | — | US | disclosed |
| CN-111132670-A | Pharmaceutical composition with enhanced penetration | 阿奎斯蒂弗医疗股份有限公司 | 2020-05-08 | — | — | CN | disclosed |
| US-9731012-B2 | Laser-actuated therapeutic nanoparticles | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-08-15 | — | — | US | disclosed |
| US-9554989-B2 | Silk reservoirs for drug delivery | TRUSTEES OF TUFTS COLLEGE (US) | 2017-01-31 | — | — | US | disclosed |
| US-20150065685-A1 | LASER-ACTUATED THERAPEUTIC NANOPARTICLES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2015-03-05 | — | — | US | disclosed |
| US-20150045764-A1 | SILK RESERVOIRS FOR DRUG DELIVERY | TRUSTEES OF TUFTS COLLEGE | 2015-02-12 | — | — | US | disclosed |
| EP-2827884-A1 | SILK RESERVOIRS FOR DRUG DELIVERY | Trustees Of Tufts College (US) | 2015-01-28 | — | — | EP | disclosed |
| WO-2013148158-A1 | LASER-ACTUATED THERAPEUTIC NANOPARTICLES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-10-03 | — | — | WO | disclosed |
| WO-2013142119-A1 | SILK RESERVOIRS FOR DRUG DELIVERY | TRUSTEES OF TUFTS COLLEGE (US) | 2013-09-26 | — | — | WO | disclosed |
| CN-101553210-A | Method and system for delivering a drug via inhalation | NEXT SAFETY INC (US) | 2009-10-07 | — | — | CN | disclosed |
| EP-1911481-A2 | Methods and systems of delivering medication via inhalation | Next Safety, Inc. (US) | 2008-04-16 | — | — | EP | disclosed |