SCHEMBL10165569

SCHEMBL10165569

COc1ccc2c3ccc(-c4ccc5c6ccc(OC)cc6n(-c6ccccc6)c5c4)cc3n(-c3ccccc3)c2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EDNRA P25101 2/20 0.50
KDM4E B2RXH2 3/20 0.48
HTT P42858 3/20 0.47
MAPT P10636 2/20 0.47
ALDH1A1 P00352 4/20 0.47
HPGD P15428 3/20 0.47
MAPK1 P28482 1/20 0.47
MAPK10 P53779 1/20 0.47
NCOA1 Q15788 1/20 0.47
NCOA3 Q9Y6Q9 1/20 0.47
KDR P35968 1/20 0.46
OXTR P30559 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
HSD17B10 Q99714 1/20 0.45
GLA P06280 1/20 0.44
ATM Q13315 1/20 0.44
NPSR1 Q6W5P4 2/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10134264 0.89 EDNRA (0.46) EDNRAKDM4EHTTMAPTALDH1A1
SCHEMBL25613235 0.89 KDM4E (0.60) EDNRAKDM4EHTTMAPTALDH1A1
SCHEMBL13241209 0.87 OXTR (0.50) EDNRAKDM4EHTTMAPTALDH1A1
SCHEMBL16171573 0.87 KDM4E (0.50) EDNRAKDM4EHTTMAPTALDH1A1
SCHEMBL16171564 0.86 KDM4E (0.54) EDNRAKDM4EHTTMAPTALDH1A1
SCHEMBL16171561 0.86 KDM4E (0.54) EDNRAKDM4EHTTMAPTALDH1A1
SCHEMBL15953618 0.86 PIN1 (0.45) EDNRAKDM4EHTTMAPTALDH1A1
SCHEMBL16171531 0.85 KDM4E (0.52) EDNRAKDM4EHTTMAPTALDH1A1
SCHEMBL16171530 0.85 KDM4E (0.52) EDNRAKDM4EHTTMAPTALDH1A1
SCHEMBL15953281 0.84 ABL1 (0.44) EDNRAKDM4EHTTMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150129861-A1 ORGANIC MATERIAL FOR DEPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, DEPOSITION METHOD, AND MANUFACTURING METHOD FOR ORGANIC PHOTOELECTRONIC ONVERSION ELEMENT OBTAINED USING THE SAME FUJIFILM CORPORATION (JP) 2015-05-14 US disclosed
US-8847141-B2 Photoelectric conversion element, production method thereof, photosensor, imaging device and their driving method FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD FUJIFILM CORPORATION (JP) 2012-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD SUN2, CYBA, PPOX EDNRA 2805/4885KDM4E 169/4885HTT 3721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.