Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10975584 | 0.83 | MAPK1 (0.41) | MAPK1KDM4EALOX15BCL2BCL2L2 | |
| SCHEMBL28502906 | 0.80 | DNMT1 (0.42) | MAPK1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL988202 | 0.79 | MAPK1 (0.52) | MAPK1KDM4EALOX15BCL2BCL2L2 | |
| SCHEMBL987319 | 0.79 | MAPK1 (0.52) | MAPK1KDM4EALOX15BCL2BCL2L2 | |
| SCHEMBL30299427 | 0.78 | MAPK1 (0.73) | MAPK1KDM4EALOX15MEN1KMT2A | |
| SCHEMBL2272378 | 0.78 | MAPK1 (0.73) | MAPK1KDM4EALOX15MEN1KMT2A | |
| SCHEMBL2271232 | 0.78 | MAPK1 (0.73) | MAPK1KDM4EALOX15MEN1KMT2A | |
| SCHEMBL1158089 | 0.78 | MAPK1 (0.73) | MAPK1KDM4EALOX15MEN1KMT2A | |
| SCHEMBL43970 | 0.77 | PTPN1 (0.42) | MAPK1KDM4EDNMT1ALDH1A1TP53 | |
| SCHEMBL8835130 | 0.77 | KDM4E (0.60) | MAPK1KDM4EALOX15MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940877-A4 | MODIFIED BIODEGRADABLE POLYMERS, PREPARATION AND USE THEREOF FOR MAKING BIOMATERIALS AND DRESSINGS | BUI-KHAC TRUNG (CA) | 2009-08-19 | — | — | EP | disclosed |
| US-20090035356-A1 | MODIFIED BIODEGRADABLE POLYMERS, PREPARATION AND USE THEREOF FOR MAKING BIOMATERIALS AND DRESSINGS | BUI-KHAC TRUNG | 2009-02-05 | — | — | US | disclosed |
| EP-1940877-A1 | MODIFIED BIODEGRADABLE POLYMERS, PREPARATION AND USE THEREOF FOR MAKING BIOMATERIALS AND DRESSINGS | Bui-Khac, Trung (CA) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007028244-A1 | MODIFIED BIODEGRADABLE POLYMERS, PREPARATION AND USE THEREOF FOR MAKING BIOMATERIALS AND DRESSINGS | BUI-KHAC TRUNG (CA) | 2007-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090035356-A1 | MODIFIED BIODEGRADABLE POLYMERS, PREPARATION AND USE THEREOF FOR MAKING BIOMATERIALS AND DRESSINGS | FIBP, CFD, COL14A1 | MAPK1 1394/4885KDM4E 2256/4885ALOX15 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.