Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.67 |
| ▸ | CYP11B1 | P15538 | 12/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | QPCT | Q16769 | 1/20 | 0.58 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.58 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylimidazole SCHEMBL6784009 | 0.88 | CYP11B1 (0.77) | TBXAS1CYP11B1CYP11B2CYP19A1CYP1A2 | |
| SCHEMBL11047192 | 0.85 | TBXAS1 (0.64) | TBXAS1CYP11B1CYP11B2ADRA2CCYP19A1 | |
| Ethylene SCHEMBL10731251 | 0.85 | TBXAS1 (0.52) | TBXAS1CYP11B1CYP11B2ADRA2CCYP19A1 | |
| SCHEMBL394308 | 0.84 | CYP11B1 (0.83) | TBXAS1CYP11B1CYP11B2ADRA2CCYP19A1 | |
| SCHEMBL7385323 | 0.83 | TBXAS1 (0.69) | TBXAS1CYP11B1CYP11B2ADRA2CCYP19A1 | |
| SCHEMBL8404966 | 0.83 | TBXAS1 (0.69) | TBXAS1CYP11B1CYP11B2ADRA2CCYP19A1 | |
| SCHEMBL9401580 | 0.82 | TBXAS1 (0.68) | TBXAS1CYP11B1CYP11B2ADRA2CCYP19A1 | |
| SCHEMBL7291119 | 0.82 | TBXAS1 (0.68) | TBXAS1CYP11B1CYP11B2ADRA2CCYP19A1 | |
| SCHEMBL210793 | 0.82 | CYP11B1 (0.69) | TBXAS1CYP11B1CYP11B2CYP19A1CYP1A2 | |
| SCHEMBL7299635 | 0.80 | TBXAS1 (0.69) | TBXAS1CYP11B1CYP11B2ADRA2CCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |
| EP-0169408-B1 | IMIDAZOLYL COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DRUGS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-31 | — | — | EP | disclosed |
| US-4665080-A | THROMBOXANE SYNTHETASE INHIBITORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-05-12 | — | — | US | disclosed |
| EP-0169408-A1 | Imidazolyl compounds, process for their preparation and their use as drugs | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-29 | — | — | EP | disclosed |