Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 10/20 | 0.69 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.66 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.66 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | QPCT | Q16769 | 1/20 | 0.62 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.62 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.62 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylimidazole SCHEMBL6784009 | 0.88 | CYP11B1 (0.77) | CYP11B1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1024261 | 0.87 | CYP11B1 (0.84) | CYP11B1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29239325 | 0.86 | CYP11B1 (0.66) | CYP11B1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6057476 | 0.85 | CYP11B1 (0.75) | CYP11B1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL1775141 | 0.85 | CYP11B1 (0.81) | CYP11B1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6940691 | 0.84 | CYP11B1 (0.64) | CYP11B1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL28482452 | 0.83 | CYP11B1 (0.62) | CYP11B1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2728383 | 0.83 | CYP11B1 (1.00) | CYP11B1CYP11B2 | |
| Ethylene SCHEMBL10731121 | 0.83 | CYP11B1 (0.52) | CYP11B1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8405925 | 0.82 | TBXAS1 (0.66) | CYP11B1TBXAS1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4041478-A | — | — | None | — | — | JP | disclosed |
| CN-118005563-A | N-benzyl imidazole derivative and preparation method and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |
| US-11034780-B2 | 1,3-dipolar compound bearing an imidazole functional group | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2021-06-15 | — | — | US | disclosed |
| US-11034780-B2 | 1,3-dipolar compound bearing an imidazole functional group | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2021-06-15 | — | — | US | disclosed |
| EP-3060552-B1 | 1,3-DIPOLAR COMPOUND BEARING AN IMIDAZOLE FUNCTION AND PROCESS FOR MODIFYING AN UNSATURATED POLYMER BY GRAFTING | MICHELIN & CIE (FR) | 2020-12-02 | — | — | EP | disclosed |
| EP-3060552-B1 | 1,3-DIPOLAR COMPOUND BEARING AN IMIDAZOLE FUNCTION AND PROCESS FOR MODIFYING AN UNSATURATED POLYMER BY GRAFTING | MICHELIN & CIE (FR) | 2020-12-02 | — | — | EP | disclosed |
| US-20190119412-A1 | 1,3-DIPOLAR COMPOUND BEARING AN IMIDAZOLE FUNCTIONAL GROUP | MICHELIN & CIE (FR) | 2019-04-25 | — | — | US | disclosed |
| US-20190119412-A1 | 1,3-DIPOLAR COMPOUND BEARING AN IMIDAZOLE FUNCTIONAL GROUP | MICHELIN & CIE (FR) | 2019-04-25 | — | — | US | disclosed |
| US-10202471-B2 | 1,3-dipolar compound bearing an imidazole functional group | COMPAGNIE GENERALE DES ETABLISSMENTS MICHELIN (FR) | 2019-02-12 | — | — | US | disclosed |
| US-10202471-B2 | 1,3-dipolar compound bearing an imidazole functional group | COMPAGNIE GENERALE DES ETABLISSMENTS MICHELIN (FR) | 2019-02-12 | — | — | US | disclosed |
| EP-1963315-A2 | ENZYME INHIBITORS | The Institute of Cancer Research (GB) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007072017-A2 | ENZYME INHIBITORS | THE INSTITUTE OF CANCER RESEARCH (GB) | 2007-06-28 | — | — | WO | disclosed |
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |
| JP-H0441478-A | PRODUCTION OF 3-(4-1-IMIDAZOLYLMETHYL)PHENYL)-2-PROPENE-1-OL | FUJIREBIO INC | 1992-02-12 | — | — | JP | disclosed |
| EP-0320984-A2 | 1,4-Dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1989-06-21 | — | — | EP | disclosed |
| EP-0169408-B1 | IMIDAZOLYL COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DRUGS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-31 | — | — | EP | disclosed |
| US-4665080-A | THROMBOXANE SYNTHETASE INHIBITORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-05-12 | — | — | US | disclosed |
| EP-0169408-A1 | Imidazolyl compounds, process for their preparation and their use as drugs | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10202471-B2 | 1,3-dipolar compound bearing an imidazole functional group | TBCB, CCNB1, H1-0 | CYP11B1 1013/4885TBXAS1 204/4885CYP1A2 1143/4885 |
| US-11034780-B2 | 1,3-dipolar compound bearing an imidazole functional group | TBCB, CCNB1, H1-0 | CYP11B1 1013/4885TBXAS1 204/4885CYP1A2 1143/4885 |
| US-20190119412-A1 | 1,3-DIPOLAR COMPOUND BEARING AN IMIDAZOLE FUNCTIONAL GROUP | TBCB, CCNB1, H1-0 | CYP11B1 1013/4885TBXAS1 204/4885CYP1A2 1143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.