Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952989 | 0.87 | KDM1A (0.48) | KDM1APTGER1ALDH1A1GAAENPP2 | |
| SCHEMBL29955141 | 0.81 | ALDH1A1 (0.49) | KDM1AALDH1A1GAAADORA3 | |
| SCHEMBL12538847 | 0.81 | ALDH1A1 (0.49) | KDM1AALDH1A1GAAADORA3 | |
| SCHEMBL2006689 | 0.81 | TSHR (0.53) | GAAENPP2CYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL2553619 | 0.80 | ALDH1A1 (0.44) | KDM1AALDH1A1GAA | |
| SCHEMBL3727775 | 0.79 | KDM1A (0.54) | KDM1APTGER1ALDH1A1GAATBXA2R | |
| SCHEMBL9967704 | 0.79 | KDM1A (0.56) | KDM1AALDH1A1GAACYP1A2CYP2D6 | |
| SCHEMBL2635090 | 0.78 | KDM4E (0.48) | PTGER1ALDH1A1GAAENPP2TP53 | |
| SCHEMBL29955101 | 0.78 | ENPP2 (0.44) | ALDH1A1ENPP2LMNASMN1; SMN2 | |
| SCHEMBL16348386 | 0.78 | ENPP2 (0.44) | ALDH1A1ENPP2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099177-A1 | PYRIDYL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-04-16 | — | — | US | disclosed |
| US-20090099177-A1 | PYRIDYL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-04-16 | — | — | US | disclosed |
| US-20090099177-A1 | PYRIDYL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-04-16 | — | — | US | disclosed |
| EP-2013181-A1 | PYRIDYL COMPOUNDS | Glaxo Group Limited (GB) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007128752-A1 | PYRIDYL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2007-11-15 | — | — | WO | disclosed |
| WO-2007128752-A1 | PYRIDYL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2007-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099177-A1 | PYRIDYL COMPOUNDS | CYP2C19, CYP4F3, C5 | KDM1A 2430/4885PTGER1 180/4885ALDH1A1 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.