⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770060 | 0.62 | — | — | |
| SCHEMBL23750954 | 0.62 | — | — | |
| SCHEMBL23750909 | 0.60 | MPO (0.41) | — | |
| SCHEMBL5444655 | 0.58 | ALDH1A1 (0.49) | — | |
| SCHEMBL23762842 | 0.57 | MPO (0.38) | — | |
| SCHEMBL7177869 | 0.57 | MAPT (0.38) | — | |
| SCHEMBL23762843 | 0.57 | MPO (0.38) | — | |
| SCHEMBL23762885 | 0.57 | MPO (0.38) | — | |
| SCHEMBL16920694 | 0.53 | MPO (0.46) | — | |
| SCHEMBL17086628 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325992-A1 | COMPOUND HAVING CYCLIC GROUP BOUND THERETO THROUGH SPIRO BINDING AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-12-31 | — | — | US | disclosed |
| EP-2055705-A1 | COMPOUND HAVING CYCLIC GROUP BOUND THERETO THROUGH SPIRO BINDING AND USE THEREOF | Ono Pharmaceutical CO., LTD. (JP) | 2009-05-06 | — | — | EP | disclosed |